FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3146073288> ?p ?o ?g. }

• W3146073288 endingPage "101296" @default.
• W3146073288 startingPage "101296" @default.
• W3146073288 abstract "Understanding the mechanical behaviors of nanoparticles confined between adjacent cells is of fundamental importance to the passage of drug cargoes through cell junctions, where the nanoparticles could have contact with two cell membranes simultaneously. Here we theoretically investigate the adhesive membrane wrapping and trapping of rigid cylindrical and spherical nanoparticles confined by two cell membranes. It is shown that the system energy and configurations depend collectively on the membrane bending rigidity, tension, adhesion energy, and the ratio between the particle size and intermembrane distance. Two fundamental modes of particle–membrane interaction are revealed, two-membrane trapping and single-membrane wrapping. Confined cylindrical nanoparticles remain trapped by two cell membranes and confined spherical nanoparticles could undergo a state transition from two-membrane trapping to single-membrane wrapping as the wrapping degree increases. Corresponding interaction phase diagrams for cylindrical and spherical nanoparticles are established based on the stability of no-wrapping, partial-trapping, partial-wrapping, full-trapping and full-wrapping states. Analytical predictions are also obtained in characterizing the single-membrane wrapping at early wrapping degree. Our results suggest that cylindrical nanoparticles in comparison with spherical nanoparticles might display superior drug penetration in tumors and across epithelial and endothelial barriers, providing guidance in the rational design of anticancer nanomedicine." @default.
• W3146073288 created "2021-04-13" @default.
• W3146073288 creator A5045427011 @default.
• W3146073288 creator A5046852308 @default.
• W3146073288 date "2021-07-01" @default.
• W3146073288 modified "2023-10-18" @default.
• W3146073288 title "Mechanics of cell interaction with intercellular nanoparticles: Shape-dependent competition between two-membrane trapping and single-membrane wrapping" @default.
• W3146073288 cites W1414886268 @default.
• W3146073288 cites W1636022800 @default.
• W3146073288 cites W1872980372 @default.
• W3146073288 cites W1964969305 @default.
• W3146073288 cites W1984680345 @default.
• W3146073288 cites W1987524026 @default.
• W3146073288 cites W2005585148 @default.
• W3146073288 cites W2010955150 @default.
• W3146073288 cites W2023888329 @default.
• W3146073288 cites W2030642623 @default.
• W3146073288 cites W2031378691 @default.
• W3146073288 cites W2067257899 @default.
• W3146073288 cites W2077506234 @default.
• W3146073288 cites W2092412094 @default.
• W3146073288 cites W2104808978 @default.
• W3146073288 cites W2116802964 @default.
• W3146073288 cites W2137925796 @default.
• W3146073288 cites W2149196822 @default.
• W3146073288 cites W2152366705 @default.
• W3146073288 cites W2264936970 @default.
• W3146073288 cites W2321663835 @default.
• W3146073288 cites W2327375394 @default.
• W3146073288 cites W2522465688 @default.
• W3146073288 cites W2556999389 @default.
• W3146073288 cites W2614943507 @default.
• W3146073288 cites W2782497225 @default.
• W3146073288 cites W2788099605 @default.
• W3146073288 cites W2811460842 @default.
• W3146073288 cites W2905475792 @default.
• W3146073288 cites W2915542383 @default.
• W3146073288 cites W2922030932 @default.
• W3146073288 cites W2966527007 @default.
• W3146073288 cites W2977303171 @default.
• W3146073288 cites W2999624514 @default.
• W3146073288 cites W3025854848 @default.
• W3146073288 cites W3110461132 @default.
• W3146073288 doi "https://doi.org/10.1016/j.eml.2021.101296" @default.
• W3146073288 hasPublicationYear "2021" @default.
• W3146073288 type Work @default.
• W3146073288 sameAs 3146073288 @default.
• W3146073288 citedByCount "2" @default.
• W3146073288 countsByYear W31460732882021 @default.
• W3146073288 countsByYear W31460732882022 @default.
• W3146073288 crossrefType "journal-article" @default.
• W3146073288 hasAuthorship W3146073288A5045427011 @default.
• W3146073288 hasAuthorship W3146073288A5046852308 @default.
• W3146073288 hasConcept C12554922 @default.
• W3146073288 hasConcept C127413603 @default.
• W3146073288 hasConcept C155672457 @default.
• W3146073288 hasConcept C159467904 @default.
• W3146073288 hasConcept C159985019 @default.
• W3146073288 hasConcept C171250308 @default.
• W3146073288 hasConcept C185592680 @default.
• W3146073288 hasConcept C18903297 @default.
• W3146073288 hasConcept C192562407 @default.
• W3146073288 hasConcept C2777924906 @default.
• W3146073288 hasConcept C2778106830 @default.
• W3146073288 hasConcept C41625074 @default.
• W3146073288 hasConcept C42475967 @default.
• W3146073288 hasConcept C55493867 @default.
• W3146073288 hasConcept C80107235 @default.
• W3146073288 hasConcept C84416704 @default.
• W3146073288 hasConcept C86803240 @default.
• W3146073288 hasConceptScore W3146073288C12554922 @default.
• W3146073288 hasConceptScore W3146073288C127413603 @default.
• W3146073288 hasConceptScore W3146073288C155672457 @default.
• W3146073288 hasConceptScore W3146073288C159467904 @default.
• W3146073288 hasConceptScore W3146073288C159985019 @default.
• W3146073288 hasConceptScore W3146073288C171250308 @default.
• W3146073288 hasConceptScore W3146073288C185592680 @default.
• W3146073288 hasConceptScore W3146073288C18903297 @default.
• W3146073288 hasConceptScore W3146073288C192562407 @default.
• W3146073288 hasConceptScore W3146073288C2777924906 @default.
• W3146073288 hasConceptScore W3146073288C2778106830 @default.
• W3146073288 hasConceptScore W3146073288C41625074 @default.
• W3146073288 hasConceptScore W3146073288C42475967 @default.
• W3146073288 hasConceptScore W3146073288C55493867 @default.
• W3146073288 hasConceptScore W3146073288C80107235 @default.
• W3146073288 hasConceptScore W3146073288C84416704 @default.
• W3146073288 hasConceptScore W3146073288C86803240 @default.
• W3146073288 hasFunder F4320321001 @default.
• W3146073288 hasLocation W31460732881 @default.
• W3146073288 hasOpenAccess W3146073288 @default.
• W3146073288 hasPrimaryLocation W31460732881 @default.
• W3146073288 hasRelatedWork W1997869797 @default.
• W3146073288 hasRelatedWork W2010109767 @default.
• W3146073288 hasRelatedWork W2024749749 @default.
• W3146073288 hasRelatedWork W2032161274 @default.
• W3146073288 hasRelatedWork W2069222261 @default.
• W3146073288 hasRelatedWork W2079733268 @default.
• W3146073288 hasRelatedWork W2323620115 @default.

• next