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- W3197659979 abstract "The incidence of acute myocardial infarction (AMI) is currently increasing. Early detection is important for the treatment and prognosis of patients with AMI. Heart‑type fatty acid‑binding protein (H‑FABP) may be used as an early marker of AMI due to its high sensitivity, specificity and prognostic value. Therefore, in the present study, H‑FABP was used as a biomarker in a double‑antibody sandwich method and colloidal gold‑based lateral flow immunoassay to develop a rapid detection kit for H‑FABP with a processing time of only 5 min. The sensitivity of the kit in plasma and whole blood was 1 ng/ml and this method had good specificity, exhibiting no cross‑reaction with cardiac troponin I, myoglobin or creatine kinase‑Mb. The kits had good shelf life and stability, as they were able to be stored at 40˚C for 30 days. A total of 12 clinical samples were collected for detection and the coincidence rate with the ELISA method was up to 91.67%. Therefore, the present study provided a simple, rapid and economical early‑detection in‑home testing kit." @default.
- W3197659979 created "2021-09-13" @default.
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- W3197659979 date "2021-08-31" @default.
- W3197659979 modified "2023-09-27" @default.
- W3197659979 title "Rapid detection of human heart‑type fatty acid‑binding protein in human plasma and blood using a colloidal gold‑based lateral flow immunoassay" @default.
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- W3197659979 doi "https://doi.org/10.3892/etm.2021.10673" @default.
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