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- W3206744218 abstract "Psoriatic arthritis (PsA) is an inflammatory form of arthritis that appears approximately 7–10 years after psoriasis and remains undiagnosed in most of patients. Currently, only a few quantitative and succinct PsA-risk prediction models are available. The aim of this study was to establish and validate a prediction model for quantitatively assessing the risk of PsA in moderate and severe plaque psoriasis patients. A non-interventional and cross-sectional study was conducted. Demographic, clinical, and laboratory records were collected and blindly reviewed. Logistic regression was used to develop this prediction model. With C-index and calibration curve, internal validation was performed. Five-fold cross validation, external validation and decision curve analysis (DCA) were also applied to assess this model. Among 405 patients, 111 patients had PsA. Arthralgia (OR = 39.346; 95% CI: 20.139–82.579), C-reactive protein (OR = 2.008; 95% CI: 1.051–3.838), lymphocyte level (OR = 0.341; 95% CI: 0.177–0.621), hypertension (OR = 0.235; 95% CI: 0.077–0.660) and disease duration (OR = 1.033; 95% CI: 0.998–1.071) were identified as potential predictors affecting the risk of transition from moderate and severe PsO to PsA. C-index for the prediction nomogram was 0.911 (95% CI: 0.879–0.943), and was confirmed to be 0.905 through 1000-time bootstrapping internal validation. Cross validation and external validation were preformed and proved the accuracy and generalizability of this prediction model. This study establishes a quantitative predictive nomogram with good predictive power for assessing the risk of PsA in patients with moderate and severe PsO." @default.
- W3206744218 created "2021-10-25" @default.
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- W3206744218 date "2021-08-01" @default.
- W3206744218 modified "2023-10-17" @default.
- W3206744218 title "Nomogram for accurate and quantitative prediction of the risk of psoriatic arthritis in Chinese adult patients with moderate and severe plaque psoriasis" @default.
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- W3206744218 doi "https://doi.org/10.1684/ejd.2021.4095" @default.
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