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- W4200437823 abstract "Fluorescence lifetime imaging provides more possibility of in vivo multiplexing in second near infrared (NIR-II) window. However, it still faces the obstacle that fluorescent probes with differentiable lifetime often exhibit quite different fluorescence intensity, especially the short lifetime usually accompanies with a weak fluorescence intensity, resulting in the difficulty for simultaneously decoding multiplexed lifetime information due to the interference of background noise. To facilitate high-fidelity lifetime multiplexed imaging, we developed a series of Er3+ doped double interface fluorescent nanoprobes (Er-DINPs): α-NaYF4@NaErF4: Ce@NaYbF4@NaErF4: Ce@NaYF4 with strong fluorescence intensity and easily distinguishable fluorescence lifetime. Both in vitro and in vivo experimental results confirmed the advantage of these probes with comparable fluorescence intensity for high-fidelity multiplexed lifetime bioimaging." @default.
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- W4200437823 date "2021-09-29" @default.
- W4200437823 modified "2023-10-15" @default.
- W4200437823 title "High‐Fidelity NIR‐II Multiplexed Lifetime Bioimaging with Bright Double Interfaced Lanthanide Nanoparticles" @default.
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- W4200437823 doi "https://doi.org/10.1002/ange.202108124" @default.
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