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- W4200508768 abstract "Herein, we report the first example of green synthesis of hybridized 1,3-cyclohexadiene (1,3-CHD) scaffolds in moderate to excellent yields. The catalyst-free sequential four-component reaction of 2-chloroquinoline-3-carbaldehydes, 1-phenyl-2-(1,1,1-triphenyl-λ5-phosphanylidene)ethan-1-one, ethyl acetoacetate and primary amine in ethanol afforded tetrasubstituted 1,3-cyclohexadienes bearing 2-oxo-1,2-dihydroquinoline moiety during 4 hours. The structure of the synthesized products was determined via X-ray analysis. This approach is characterized by its operational simplicity, readily available precursors, green solvent, mild conditions, and moderate to excellent yields." @default.
- W4200508768 created "2021-12-31" @default.
- W4200508768 creator A5001184084 @default.
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- W4200508768 date "2021-12-03" @default.
- W4200508768 modified "2023-10-06" @default.
- W4200508768 title "Synthesis of Novel 1,3‐Cyclohexadiene Derivatives Bearing 2‐Oxo‐Quinoline Moiety <i>via</i> a 4‐CR Strategy**" @default.
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- W4200508768 doi "https://doi.org/10.1002/slct.202103240" @default.
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