Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200576775> ?p ?o ?g. }
- W4200576775 abstract "Ferroptosis, an iron-dependent form of non-apoptotic cell death, is believed to strongly contribute to the pathogenesis of multiple cancers. Recently, the positive association between ferroptosis and urologic malignancies has drawn considerable attention, while a comprehensive review focused on this issue is absent. Based on this review, ferroptosis has been implicated in the development and therapeutic responses of prostate cancer, kidney cancer, and bladder cancer. Mechanistically, a large number of biomolecules and tumor-associated signaling pathways, including DECR1, PANX2, HSPB1, ACOT8, SUV39H1, NCOA4, PI3K-AKT-mTOR signaling, VHL/HIF-2α pathway, and Hippo/TAZ signaling pathway, have been reported to regulate ferroptosis in urologic cancers. Ferroptosis inducers, such as erastin, ART, CPNPs, and quinazolinyl-arylurea derivatives, exert potential therapeutic effects per se and/or enhance the anticancer response of other anticancer drugs in urologic oncology. A better understanding of ferroptosis may provide a promising way to treat therapy-resistant urologic cancers." @default.
- W4200576775 created "2021-12-31" @default.
- W4200576775 creator A5001506483 @default.
- W4200576775 creator A5022526821 @default.
- W4200576775 creator A5028490070 @default.
- W4200576775 creator A5037203997 @default.
- W4200576775 creator A5043958833 @default.
- W4200576775 creator A5053137351 @default.
- W4200576775 creator A5084714941 @default.
- W4200576775 date "2021-12-18" @default.
- W4200576775 modified "2023-10-18" @default.
- W4200576775 title "Roles of ferroptosis in urologic malignancies" @default.
- W4200576775 cites W1970105982 @default.
- W4200576775 cites W1975279481 @default.
- W4200576775 cites W1975617209 @default.
- W4200576775 cites W1980023909 @default.
- W4200576775 cites W1992412494 @default.
- W4200576775 cites W1992921779 @default.
- W4200576775 cites W1994476571 @default.
- W4200576775 cites W1997183854 @default.
- W4200576775 cites W1999365329 @default.
- W4200576775 cites W2010505974 @default.
- W4200576775 cites W2032860037 @default.
- W4200576775 cites W2049141759 @default.
- W4200576775 cites W2057095795 @default.
- W4200576775 cites W2057632732 @default.
- W4200576775 cites W2067107606 @default.
- W4200576775 cites W2072032391 @default.
- W4200576775 cites W2078146987 @default.
- W4200576775 cites W2098937386 @default.
- W4200576775 cites W2100671540 @default.
- W4200576775 cites W2104407980 @default.
- W4200576775 cites W2104649562 @default.
- W4200576775 cites W2119851117 @default.
- W4200576775 cites W2132264180 @default.
- W4200576775 cites W2142181775 @default.
- W4200576775 cites W2146499878 @default.
- W4200576775 cites W2163005196 @default.
- W4200576775 cites W2165300664 @default.
- W4200576775 cites W2183543808 @default.
- W4200576775 cites W2264995374 @default.
- W4200576775 cites W2275679174 @default.
- W4200576775 cites W2298483423 @default.
- W4200576775 cites W2424086769 @default.
- W4200576775 cites W2513249090 @default.
- W4200576775 cites W2533374213 @default.
- W4200576775 cites W2561420332 @default.
- W4200576775 cites W2610633406 @default.
- W4200576775 cites W2613084028 @default.
- W4200576775 cites W2613165131 @default.
- W4200576775 cites W2745520112 @default.
- W4200576775 cites W2767055857 @default.
- W4200576775 cites W2767104224 @default.
- W4200576775 cites W2789924078 @default.
- W4200576775 cites W2790729376 @default.
- W4200576775 cites W2791159567 @default.
- W4200576775 cites W2800310990 @default.
- W4200576775 cites W2806219344 @default.
- W4200576775 cites W2833129054 @default.
- W4200576775 cites W2888144978 @default.
- W4200576775 cites W2896757864 @default.
- W4200576775 cites W2902075599 @default.
- W4200576775 cites W2909817598 @default.
- W4200576775 cites W2911992807 @default.
- W4200576775 cites W2913919807 @default.
- W4200576775 cites W2932111434 @default.
- W4200576775 cites W2935600278 @default.
- W4200576775 cites W2943411873 @default.
- W4200576775 cites W2945161487 @default.
- W4200576775 cites W2947327131 @default.
- W4200576775 cites W2952813992 @default.
- W4200576775 cites W2953831294 @default.
- W4200576775 cites W2972164676 @default.
- W4200576775 cites W2980720372 @default.
- W4200576775 cites W2981745349 @default.
- W4200576775 cites W2982396938 @default.
- W4200576775 cites W2982703253 @default.
- W4200576775 cites W2990226526 @default.
- W4200576775 cites W2996461479 @default.
- W4200576775 cites W3003298644 @default.
- W4200576775 cites W3008134242 @default.
- W4200576775 cites W3010927243 @default.
- W4200576775 cites W3017018359 @default.
- W4200576775 cites W3025951663 @default.
- W4200576775 cites W3027500407 @default.
- W4200576775 cites W3032961640 @default.
- W4200576775 cites W3034193580 @default.
- W4200576775 cites W3036780581 @default.
- W4200576775 cites W3037187659 @default.
- W4200576775 cites W3041162284 @default.
- W4200576775 cites W3043881770 @default.
- W4200576775 cites W3044167168 @default.
- W4200576775 cites W3044194698 @default.
- W4200576775 cites W3044383543 @default.
- W4200576775 cites W3045595202 @default.
- W4200576775 cites W3047457325 @default.
- W4200576775 cites W3049020383 @default.
- W4200576775 cites W3049040124 @default.
- W4200576775 cites W3083521997 @default.
- W4200576775 cites W3086825172 @default.