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• W4210367090 abstract "Significance This study reveals that impaired IKKα expression or activity in lung cancer enhances differentiation of protumorigenic Treg cells through a TNF/TNFR2/NF-κB signaling pathway in both human and mouse lung ADC. Depletion of one of the molecules that are required for Treg cell induction represses lung ADC development. Thus, the components that interfere with this particular Treg differentiation provide targets for the generation of TME-modifying therapies." @default.
• W4210367090 created "2022-02-08" @default.
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• W4210367090 date "2022-02-04" @default.
• W4210367090 modified "2023-10-18" @default.
• W4210367090 title "IKKα-deficient lung adenocarcinomas generate an immunosuppressive microenvironment by overproducing Treg-inducing cytokines" @default.
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• W4210367090 doi "https://doi.org/10.1073/pnas.2120956119" @default.
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