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• W4210367696 abstract "Dietary supplements (DS) for male infertility marketed in Italy were evaluated for composition, concentration of ingredients, and recommended daily dose. A systematic review of literature identified ingredients potentially effective on sperm parameters and their minimal effective daily dose (mED).This study was conducted in order to critically evaluate the composition and efficacy of DS marketed in Italy.This was a systematic review of randomized controlled trials.A formula allowed us to classify the expected efficacy of each DS, based on composition. Each DS was scored and included into three classes of expected efficacy: high, low, and none.Among 24 supplements, 3 (12.5%) fall in high, 9 (37.5%) in lower, and 12 (50.0%) in no expected efficacy class. DS composition showed 36 substances, 18 with no literature on male fertility and 18 showing positive effect on sperm parameters, thus considered potentially active ingredients (PAI). All DS were mixtures of ingredients, containing from 2 to 17 different substances. Fifteen supplements (65.2%) contained at least 1 ingredient without evidence of efficacy and 21 formulations had PAI dosed below mED. Some PAI were associated to the improvement of specific sperm parameters.DS were usually blends of many substances that are frequently employed at negligible dose or without any evidence of efficacy on male reproduction. Some ingredients have been demonstrated to be effective on specific sperm parameters by RCTs. We report a list of ingredients with potential efficacy on specific sperm parameters, aimed to allow a tailored use of DS.The market of DS for male infertility offers products with potential efficacy in the improvement of sperm parameters but also many with uncertain effects. Based on current scientific literature, our study can help in the choice of DS that are more likely to be effective on specific sperm alterations, so providing the best supplementation for each patient." @default.
• W4210367696 created "2022-02-08" @default.
• W4210367696 creator A5005998619 @default.
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• W4210367696 date "2022-02-04" @default.
• W4210367696 modified "2023-09-30" @default.
• W4210367696 title "Systematic Review and Critical Analysis on Dietary Supplements for Male Infertility: From a Blend of Ingredients to a Rationale Strategy" @default.
• W4210367696 cites W1505067859 @default.
• W4210367696 cites W1505704931 @default.
• W4210367696 cites W156975622 @default.
• W4210367696 cites W1643779414 @default.
• W4210367696 cites W1914422569 @default.
• W4210367696 cites W1966316717 @default.
• W4210367696 cites W1977722771 @default.
• W4210367696 cites W1984865540 @default.
• W4210367696 cites W1990841712 @default.
• W4210367696 cites W1995116906 @default.
• W4210367696 cites W2000505803 @default.
• W4210367696 cites W2003528941 @default.
• W4210367696 cites W2013411735 @default.
• W4210367696 cites W2015192276 @default.
• W4210367696 cites W2032057384 @default.
• W4210367696 cites W2035871628 @default.
• W4210367696 cites W2041849093 @default.
• W4210367696 cites W2043771612 @default.
• W4210367696 cites W2045218022 @default.
• W4210367696 cites W2046576161 @default.
• W4210367696 cites W2052999816 @default.
• W4210367696 cites W2054005293 @default.
• W4210367696 cites W2080529264 @default.
• W4210367696 cites W2080711916 @default.
• W4210367696 cites W2080810102 @default.
• W4210367696 cites W2081034946 @default.
• W4210367696 cites W2088276435 @default.
• W4210367696 cites W2097203767 @default.
• W4210367696 cites W2100345012 @default.
• W4210367696 cites W2104143475 @default.
• W4210367696 cites W2104675861 @default.
• W4210367696 cites W2104735494 @default.
• W4210367696 cites W2105193622 @default.
• W4210367696 cites W2108396632 @default.
• W4210367696 cites W2111028931 @default.
• W4210367696 cites W2111144101 @default.
• W4210367696 cites W2112164869 @default.
• W4210367696 cites W2118756809 @default.
• W4210367696 cites W2126936424 @default.
• W4210367696 cites W2128630157 @default.
• W4210367696 cites W2133901458 @default.
• W4210367696 cites W2135557704 @default.
• W4210367696 cites W2136016193 @default.
• W4210367696 cites W2154909608 @default.
• W4210367696 cites W2168332282 @default.
• W4210367696 cites W2169983001 @default.
• W4210367696 cites W2228555604 @default.
• W4210367696 cites W2238985794 @default.
• W4210367696 cites W2247553 @default.
• W4210367696 cites W2307096582 @default.
• W4210367696 cites W2311311479 @default.
• W4210367696 cites W2322868477 @default.
• W4210367696 cites W2346108842 @default.
• W4210367696 cites W2407522967 @default.
• W4210367696 cites W2418303376 @default.
• W4210367696 cites W2470198859 @default.
• W4210367696 cites W2544647862 @default.
• W4210367696 cites W2549241265 @default.
• W4210367696 cites W2588681363 @default.
• W4210367696 cites W2592813833 @default.
• W4210367696 cites W2622331626 @default.
• W4210367696 cites W2623283376 @default.
• W4210367696 cites W2730390274 @default.
• W4210367696 cites W2892470726 @default.
• W4210367696 cites W2893885083 @default.
• W4210367696 cites W2902174158 @default.
• W4210367696 cites W2906091402 @default.
• W4210367696 cites W2910501974 @default.
• W4210367696 cites W2915313687 @default.
• W4210367696 cites W2916841405 @default.
• W4210367696 cites W2936446594 @default.
• W4210367696 cites W2946294429 @default.
• W4210367696 cites W2970781004 @default.
• W4210367696 cites W2981556669 @default.
• W4210367696 cites W2982790384 @default.
• W4210367696 cites W2999455759 @default.
• W4210367696 cites W3008754475 @default.
• W4210367696 cites W3028101522 @default.
• W4210367696 cites W3041985484 @default.
• W4210367696 cites W3049686564 @default.
• W4210367696 cites W3118615836 @default.
• W4210367696 cites W3149113462 @default.
• W4210367696 cites W3207042087 @default.
• W4210367696 doi "https://doi.org/10.3389/fendo.2021.824078" @default.
• W4210367696 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35185789" @default.
• W4210367696 hasPublicationYear "2022" @default.
• W4210367696 type Work @default.

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