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- W4210367867 endingPage "1179" @default.
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- W4210367867 abstract "Methyltrimethoxysilane [MTM, CH3Si(OMe)3] has been demonstrated to be an effective, inexpensive, and safe reagent for the direct amidation of carboxylic acids with amines. Two simple workup procedures that provide the pure amide product without the need for further purification have been developed. The first employs an aqueous base-mediated annihilation of MTM. The second involves simple product crystallization from the reaction mixture providing a low process mass intensity direct amidation protocol." @default.
- W4210367867 created "2022-02-08" @default.
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- W4210367867 date "2022-01-27" @default.
- W4210367867 modified "2023-10-11" @default.
- W4210367867 title "Methyltrimethoxysilane (MTM) as a Reagent for Direct Amidation of Carboxylic Acids" @default.
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- W4210367867 doi "https://doi.org/10.1021/acs.orglett.1c04265" @default.
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