FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4214480918> ?p ?o ?g. }

• W4214480918 abstract "Abstract Breast cancer is one of the leading causes of mortality among women. Triple-negative breast cancer (TNBC) is responsible for a large percentage of all breast cancer deaths in women. This study demonstrated the function of Myb-like, SWIRM, and MPN domains 1 (MYSM1), an H2A deubiquitinase (DUB), in TNBC. MYSM1 expression was drastically decreased in breast cancer, especially in TNBC, suggesting a potential anticancer effect. Overexpressing and suppressing MYSM1 expression in TNBC cell lines led to significant biological changes in cell proliferation. Furthermore, MYSM1 overexpression increased cisplatin-induced apoptosis, which might be attributed to RSK3 inactivation and the subsequently decreased phosphorylation of Bcl-2 antagonist of cell death (BAD) (Ser 112). The findings suggest that MYSM1 is a potential target for regulating cell apoptosis and suppressing resistance to cisplatin in TNBC." @default.
• W4214480918 created "2022-03-02" @default.
• W4214480918 creator A5006165634 @default.
• W4214480918 creator A5022284407 @default.
• W4214480918 creator A5025035635 @default.
• W4214480918 creator A5029860536 @default.
• W4214480918 creator A5041284997 @default.
• W4214480918 creator A5048843854 @default.
• W4214480918 creator A5067669293 @default.
• W4214480918 creator A5071099621 @default.
• W4214480918 creator A5071740301 @default.
• W4214480918 creator A5074581392 @default.
• W4214480918 creator A5077600873 @default.
• W4214480918 creator A5078039491 @default.
• W4214480918 creator A5086759438 @default.
• W4214480918 date "2022-02-26" @default.
• W4214480918 modified "2023-10-14" @default.
• W4214480918 title "MYSM1 induces apoptosis and sensitizes TNBC cells to cisplatin via RSK3–phospho-BAD pathway" @default.
• W4214480918 cites W1482379864 @default.
• W4214480918 cites W1968492615 @default.
• W4214480918 cites W1976062660 @default.
• W4214480918 cites W1976441097 @default.
• W4214480918 cites W2029344766 @default.
• W4214480918 cites W2030254491 @default.
• W4214480918 cites W2033182904 @default.
• W4214480918 cites W2042625441 @default.
• W4214480918 cites W2059233607 @default.
• W4214480918 cites W2064854415 @default.
• W4214480918 cites W2079948123 @default.
• W4214480918 cites W2108412943 @default.
• W4214480918 cites W2117247812 @default.
• W4214480918 cites W2127429864 @default.
• W4214480918 cites W2134539328 @default.
• W4214480918 cites W2141000514 @default.
• W4214480918 cites W2148561037 @default.
• W4214480918 cites W2170665660 @default.
• W4214480918 cites W2234708228 @default.
• W4214480918 cites W2411438385 @default.
• W4214480918 cites W2612268936 @default.
• W4214480918 cites W2733251850 @default.
• W4214480918 cites W2736730167 @default.
• W4214480918 cites W2765224588 @default.
• W4214480918 cites W2808293799 @default.
• W4214480918 cites W2885727096 @default.
• W4214480918 cites W2970491887 @default.
• W4214480918 cites W2991546509 @default.
• W4214480918 cites W3000314003 @default.
• W4214480918 cites W3027286012 @default.
• W4214480918 cites W3029294993 @default.
• W4214480918 cites W3166485299 @default.
• W4214480918 doi "https://doi.org/10.1038/s41420-022-00881-1" @default.
• W4214480918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35217648" @default.
• W4214480918 hasPublicationYear "2022" @default.
• W4214480918 type Work @default.
• W4214480918 citedByCount "3" @default.
• W4214480918 countsByYear W42144809182022 @default.
• W4214480918 crossrefType "journal-article" @default.
• W4214480918 hasAuthorship W4214480918A5006165634 @default.
• W4214480918 hasAuthorship W4214480918A5022284407 @default.
• W4214480918 hasAuthorship W4214480918A5025035635 @default.
• W4214480918 hasAuthorship W4214480918A5029860536 @default.
• W4214480918 hasAuthorship W4214480918A5041284997 @default.
• W4214480918 hasAuthorship W4214480918A5048843854 @default.
• W4214480918 hasAuthorship W4214480918A5067669293 @default.
• W4214480918 hasAuthorship W4214480918A5071099621 @default.
• W4214480918 hasAuthorship W4214480918A5071740301 @default.
• W4214480918 hasAuthorship W4214480918A5074581392 @default.
• W4214480918 hasAuthorship W4214480918A5077600873 @default.
• W4214480918 hasAuthorship W4214480918A5078039491 @default.
• W4214480918 hasAuthorship W4214480918A5086759438 @default.
• W4214480918 hasBestOaLocation W42144809181 @default.
• W4214480918 hasConcept C121608353 @default.
• W4214480918 hasConcept C126322002 @default.
• W4214480918 hasConcept C143998085 @default.
• W4214480918 hasConcept C185592680 @default.
• W4214480918 hasConcept C190283241 @default.
• W4214480918 hasConcept C2776694085 @default.
• W4214480918 hasConcept C2778239845 @default.
• W4214480918 hasConcept C2780110267 @default.
• W4214480918 hasConcept C31573885 @default.
• W4214480918 hasConcept C502942594 @default.
• W4214480918 hasConcept C530470458 @default.
• W4214480918 hasConcept C54355233 @default.
• W4214480918 hasConcept C71924100 @default.
• W4214480918 hasConcept C86803240 @default.
• W4214480918 hasConceptScore W4214480918C121608353 @default.
• W4214480918 hasConceptScore W4214480918C126322002 @default.
• W4214480918 hasConceptScore W4214480918C143998085 @default.
• W4214480918 hasConceptScore W4214480918C185592680 @default.
• W4214480918 hasConceptScore W4214480918C190283241 @default.
• W4214480918 hasConceptScore W4214480918C2776694085 @default.
• W4214480918 hasConceptScore W4214480918C2778239845 @default.
• W4214480918 hasConceptScore W4214480918C2780110267 @default.
• W4214480918 hasConceptScore W4214480918C31573885 @default.
• W4214480918 hasConceptScore W4214480918C502942594 @default.
• W4214480918 hasConceptScore W4214480918C530470458 @default.
• W4214480918 hasConceptScore W4214480918C54355233 @default.
• W4214480918 hasConceptScore W4214480918C71924100 @default.
• W4214480918 hasConceptScore W4214480918C86803240 @default.
• W4214480918 hasFunder F4320321001 @default.

• next