Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220761721> ?p ?o ?g. }
- W4220761721 endingPage "106636" @default.
- W4220761721 startingPage "106636" @default.
- W4220761721 abstract "Inflammatory signaling pathways involving eicosanoids and other regulatory lipid mediators are a subject of intensive study, and a role for these in acute lung injury is not yet well understood. We hypothesized that oxylipin release from lung injury could be detected in bronchoalveolar lavage fluid and in plasma. In a porcine model of surfactant depletion, ventilation with hyperinflation was assessed. Bronchoalveolar lavage and plasma samples were analyzed for 37 different fatty acid metabolites (oxylipins). Over time, hyperinflation altered concentrations of 4 oxylipins in plasma (TXB2, PGE2, 15-HETE and 11-HETE), and 9 oxylipins in bronchoalveolar lavage fluid (PGF2α, PGE2, PGD2, 12,13-DiHOME, 11,12-DiHETrE, 13-HODE, 9-HODE, 15-HETE, 11-HETE). Acute lung injury caused by high tidal volume ventilation in this porcine model was associated with rapid changes in some elements of the oxylipin profile, detectable in lavage fluid, and plasma. These oxylipins may be relevant in the pathogenesis of acute lung injury by hyperinflation." @default.
- W4220761721 created "2022-04-03" @default.
- W4220761721 creator A5009200725 @default.
- W4220761721 creator A5011753749 @default.
- W4220761721 creator A5021509430 @default.
- W4220761721 creator A5038790904 @default.
- W4220761721 creator A5060002453 @default.
- W4220761721 creator A5070304651 @default.
- W4220761721 creator A5083867995 @default.
- W4220761721 creator A5088331171 @default.
- W4220761721 date "2022-06-01" @default.
- W4220761721 modified "2023-09-25" @default.
- W4220761721 title "Plasma and bronchoalveolar lavage fluid oxylipin levels in experimental porcine lung injury" @default.
- W4220761721 cites W1539392991 @default.
- W4220761721 cites W1766122222 @default.
- W4220761721 cites W1800893716 @default.
- W4220761721 cites W1815828750 @default.
- W4220761721 cites W1939723417 @default.
- W4220761721 cites W1978083802 @default.
- W4220761721 cites W1990202497 @default.
- W4220761721 cites W1990819855 @default.
- W4220761721 cites W1999115955 @default.
- W4220761721 cites W2005239390 @default.
- W4220761721 cites W2006634108 @default.
- W4220761721 cites W2013641792 @default.
- W4220761721 cites W2014169018 @default.
- W4220761721 cites W2017683119 @default.
- W4220761721 cites W2027413649 @default.
- W4220761721 cites W2040274576 @default.
- W4220761721 cites W2045770017 @default.
- W4220761721 cites W2051966525 @default.
- W4220761721 cites W2064769063 @default.
- W4220761721 cites W2065294999 @default.
- W4220761721 cites W2066370401 @default.
- W4220761721 cites W2079694536 @default.
- W4220761721 cites W2094368294 @default.
- W4220761721 cites W2095647610 @default.
- W4220761721 cites W2102252008 @default.
- W4220761721 cites W2108571061 @default.
- W4220761721 cites W2113752525 @default.
- W4220761721 cites W2114722789 @default.
- W4220761721 cites W2115045616 @default.
- W4220761721 cites W2115125787 @default.
- W4220761721 cites W2119394391 @default.
- W4220761721 cites W2145630011 @default.
- W4220761721 cites W2146082012 @default.
- W4220761721 cites W2148958087 @default.
- W4220761721 cites W2153339769 @default.
- W4220761721 cites W2163053457 @default.
- W4220761721 cites W2167743972 @default.
- W4220761721 cites W2171714447 @default.
- W4220761721 cites W2172212174 @default.
- W4220761721 cites W2195892184 @default.
- W4220761721 cites W2589360715 @default.
- W4220761721 cites W2597070792 @default.
- W4220761721 cites W3000447504 @default.
- W4220761721 cites W3073153751 @default.
- W4220761721 cites W3083862941 @default.
- W4220761721 cites W3152054847 @default.
- W4220761721 cites W4200317398 @default.
- W4220761721 doi "https://doi.org/10.1016/j.prostaglandins.2022.106636" @default.
- W4220761721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35307566" @default.
- W4220761721 hasPublicationYear "2022" @default.
- W4220761721 type Work @default.
- W4220761721 citedByCount "1" @default.
- W4220761721 countsByYear W42207617212023 @default.
- W4220761721 crossrefType "journal-article" @default.
- W4220761721 hasAuthorship W4220761721A5009200725 @default.
- W4220761721 hasAuthorship W4220761721A5011753749 @default.
- W4220761721 hasAuthorship W4220761721A5021509430 @default.
- W4220761721 hasAuthorship W4220761721A5038790904 @default.
- W4220761721 hasAuthorship W4220761721A5060002453 @default.
- W4220761721 hasAuthorship W4220761721A5070304651 @default.
- W4220761721 hasAuthorship W4220761721A5083867995 @default.
- W4220761721 hasAuthorship W4220761721A5088331171 @default.
- W4220761721 hasBestOaLocation W42207617211 @default.
- W4220761721 hasConcept C126322002 @default.
- W4220761721 hasConcept C181199279 @default.
- W4220761721 hasConcept C185592680 @default.
- W4220761721 hasConcept C203014093 @default.
- W4220761721 hasConcept C2777714996 @default.
- W4220761721 hasConcept C2777961210 @default.
- W4220761721 hasConcept C2779943694 @default.
- W4220761721 hasConcept C55493867 @default.
- W4220761721 hasConcept C71924100 @default.
- W4220761721 hasConceptScore W4220761721C126322002 @default.
- W4220761721 hasConceptScore W4220761721C181199279 @default.
- W4220761721 hasConceptScore W4220761721C185592680 @default.
- W4220761721 hasConceptScore W4220761721C203014093 @default.
- W4220761721 hasConceptScore W4220761721C2777714996 @default.
- W4220761721 hasConceptScore W4220761721C2777961210 @default.
- W4220761721 hasConceptScore W4220761721C2779943694 @default.
- W4220761721 hasConceptScore W4220761721C55493867 @default.
- W4220761721 hasConceptScore W4220761721C71924100 @default.
- W4220761721 hasFunder F4320309792 @default.
- W4220761721 hasFunder F4320321615 @default.
- W4220761721 hasFunder F4320322581 @default.
- W4220761721 hasFunder F4320338438 @default.