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• W4220794713 startingPage "100856" @default.
• W4220794713 abstract "A new series of various substituted aryl and hetero aryl amide derivatives of benzoxazole linked imidazo[2,1-b][1,3,4]thiadiazole (11a-j) were synthesized and their structures confirmed by spectral data. These newly synthesized compounds (11a-j) were evaluated for their anticancer profile towards human prostate cancer (PC3 and DU-145), lung cancer (A549) and breast cancer (MCF-7) cell lines by used of MTT assay and etoposide was chosen as positive control. Most of the derivatives displayed good to moderate antiproliferative activities with respective cell lines. Among the evaluated compounds, four compounds (11a, 11b, 11c and 11d) demonstrated more potent anticancer activity. Particularly, compound 11a showed strongest activity as etoposide." @default.
• W4220794713 created "2022-04-03" @default.
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• W4220794713 date "2022-06-01" @default.
• W4220794713 modified "2023-10-16" @default.
• W4220794713 title "Synthesis and biological evaluation of amide derivatives of benzoxazole linked Imidazo[2,1-b][1,3,4]thiadiazole as antiproliferative agents" @default.
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• W4220794713 doi "https://doi.org/10.1016/j.cdc.2022.100856" @default.
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