Matches in SemOpenAlex for { <https://semopenalex.org/work/W4221036122> ?p ?o ?g. }
- W4221036122 endingPage "285" @default.
- W4221036122 startingPage "285" @default.
- W4221036122 abstract "Fungal endophytes have remarkable potential to produce bioactive compounds with numerous pharmacological significance that are used in various disease management and human welfare. In the current study, a total of eight fungal endophytes were isolated from the leaf tissue of Amoora rohituka, and out of which ethyl acetate (EA) extract of Penicillium oxalicum was found to exhibit potential antioxidant activity against DPPH, nitric oxide, superoxide anion and hydroxyl free radicals with EC50 values of 178.30 ± 1.446, 75.79 ± 0.692, 169.28 ± 0.402 and 126.12 ± 0.636 µg/mL, respectively. The significant antioxidant activity of EA extract of P. oxalicum is validated through highest phenolic and flavonoid content, and the presence of unique bioactive components observed through high-performance thin layer chromatography (HPTLC) fingerprinting. Moreover, EA extract of P. oxalicum also displayed substantial anti-proliferative activity with IC50 values of 56.81 ± 0.617, 37.24 ± 1.26 and 260.627 ± 5.415 µg/mL against three cancer cells HuT-78, MDA-MB-231 and MCF-7, respectively. Furthermore, comparative HPTLC fingerprint analysis and antioxidant activity of P. oxalicum revealed that fungal endophyte P. oxalicum produces bioactive compounds in a host-dependent manner. Therefore, the present study signifies that fungal endophyte P. oxalicum associated with the leaf of A. rohituka could be a potential source of bioactive compounds with antioxidant and anticancer activity." @default.
- W4221036122 created "2022-04-03" @default.
- W4221036122 creator A5003868818 @default.
- W4221036122 creator A5038728019 @default.
- W4221036122 creator A5044142223 @default.
- W4221036122 creator A5054451232 @default.
- W4221036122 creator A5062410282 @default.
- W4221036122 creator A5063828656 @default.
- W4221036122 creator A5065758936 @default.
- W4221036122 creator A5066372495 @default.
- W4221036122 creator A5087630101 @default.
- W4221036122 date "2022-03-10" @default.
- W4221036122 modified "2023-10-03" @default.
- W4221036122 title "Assessment of Biological Activities of Fungal Endophytes Derived Bioactive Compounds Isolated from Amoora rohituka" @default.
- W4221036122 cites W11103098 @default.
- W4221036122 cites W1817807365 @default.
- W4221036122 cites W1971570374 @default.
- W4221036122 cites W1977399717 @default.
- W4221036122 cites W1985111355 @default.
- W4221036122 cites W1988196366 @default.
- W4221036122 cites W1991775006 @default.
- W4221036122 cites W1993034915 @default.
- W4221036122 cites W1998255169 @default.
- W4221036122 cites W1999975246 @default.
- W4221036122 cites W2001486781 @default.
- W4221036122 cites W2001773626 @default.
- W4221036122 cites W2003782853 @default.
- W4221036122 cites W2017554024 @default.
- W4221036122 cites W2021800215 @default.
- W4221036122 cites W2023096068 @default.
- W4221036122 cites W2029989652 @default.
- W4221036122 cites W2055043387 @default.
- W4221036122 cites W2062257233 @default.
- W4221036122 cites W2065245764 @default.
- W4221036122 cites W2065686685 @default.
- W4221036122 cites W2065879116 @default.
- W4221036122 cites W2067670322 @default.
- W4221036122 cites W2082886600 @default.
- W4221036122 cites W2089331318 @default.
- W4221036122 cites W2095396249 @default.
- W4221036122 cites W2104360899 @default.
- W4221036122 cites W2120937999 @default.
- W4221036122 cites W2121034444 @default.
- W4221036122 cites W2124714448 @default.
- W4221036122 cites W2126938720 @default.
- W4221036122 cites W2132149755 @default.
- W4221036122 cites W2132344671 @default.
- W4221036122 cites W2136230383 @default.
- W4221036122 cites W2160360534 @default.
- W4221036122 cites W2164202552 @default.
- W4221036122 cites W2168102362 @default.
- W4221036122 cites W2171005136 @default.
- W4221036122 cites W2314490704 @default.
- W4221036122 cites W2317336769 @default.
- W4221036122 cites W2411047947 @default.
- W4221036122 cites W2549194028 @default.
- W4221036122 cites W2766324273 @default.
- W4221036122 cites W2905166701 @default.
- W4221036122 cites W2908992686 @default.
- W4221036122 cites W2918824967 @default.
- W4221036122 cites W2919643781 @default.
- W4221036122 cites W2990270528 @default.
- W4221036122 cites W2990525773 @default.
- W4221036122 cites W2996477462 @default.
- W4221036122 cites W3025398096 @default.
- W4221036122 cites W3026343222 @default.
- W4221036122 cites W3026631269 @default.
- W4221036122 cites W3083504736 @default.
- W4221036122 cites W3093739892 @default.
- W4221036122 cites W3122874823 @default.
- W4221036122 cites W3157824263 @default.
- W4221036122 cites W3174165492 @default.
- W4221036122 cites W3208377260 @default.
- W4221036122 cites W3213329523 @default.
- W4221036122 doi "https://doi.org/10.3390/jof8030285" @default.
- W4221036122 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35330287" @default.
- W4221036122 hasPublicationYear "2022" @default.
- W4221036122 type Work @default.
- W4221036122 citedByCount "18" @default.
- W4221036122 countsByYear W42210361222022 @default.
- W4221036122 countsByYear W42210361222023 @default.
- W4221036122 crossrefType "journal-article" @default.
- W4221036122 hasAuthorship W4221036122A5003868818 @default.
- W4221036122 hasAuthorship W4221036122A5038728019 @default.
- W4221036122 hasAuthorship W4221036122A5044142223 @default.
- W4221036122 hasAuthorship W4221036122A5054451232 @default.
- W4221036122 hasAuthorship W4221036122A5062410282 @default.
- W4221036122 hasAuthorship W4221036122A5063828656 @default.
- W4221036122 hasAuthorship W4221036122A5065758936 @default.
- W4221036122 hasAuthorship W4221036122A5066372495 @default.
- W4221036122 hasAuthorship W4221036122A5087630101 @default.
- W4221036122 hasBestOaLocation W42210361221 @default.
- W4221036122 hasConcept C185592680 @default.
- W4221036122 hasConcept C202751555 @default.
- W4221036122 hasConcept C2777525088 @default.
- W4221036122 hasConcept C2777752497 @default.
- W4221036122 hasConcept C2778004101 @default.
- W4221036122 hasConcept C2779054382 @default.