Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225114089> ?p ?o ?g. }
- W4225114089 abstract "The repair and motor functional recovery after spinal cord injury (SCI) has remained a clinical challenge. Injury-induced gliosis and inflammation lead to a physical barrier and an extremely inhibitory microenvironment, which in turn hinders the recovery of SCI. TLR4-NF-κB is a classic implant-related innate immunomodulation signaling pathway and part of numerous biomaterial-based treatment strategies for SCI. Numerous experimental studies have demonstrated that the regulation of TLR4-NF-κB signaling pathway plays an important role in the alleviation of inflammatory responses, the modulation of autophagy, apoptosis and ferroptosis, and the enhancement of anti-oxidative effect post-SCI. An increasing number of novel biomaterials have been fabricated as scaffolds and carriers, loaded with phytochemicals and drugs, to inhibit the progression of SCI through regulation of TLR4-NF-κB. This review summarizes the empirical strategies for the recovery after SCI through individual or composite biomaterials that mediate the TLR4-NF-κB signaling pathway." @default.
- W4225114089 created "2022-05-01" @default.
- W4225114089 creator A5009825671 @default.
- W4225114089 creator A5011517981 @default.
- W4225114089 creator A5021232742 @default.
- W4225114089 creator A5031639923 @default.
- W4225114089 creator A5032581278 @default.
- W4225114089 creator A5053248743 @default.
- W4225114089 creator A5057838726 @default.
- W4225114089 creator A5082762112 @default.
- W4225114089 date "2022-04-29" @default.
- W4225114089 modified "2023-09-30" @default.
- W4225114089 title "Strategies for Biomaterial-Based Spinal Cord Injury Repair via the TLR4-NF-κB Signaling Pathway" @default.
- W4225114089 cites W1517869221 @default.
- W4225114089 cites W1523693806 @default.
- W4225114089 cites W1527455107 @default.
- W4225114089 cites W1628197608 @default.
- W4225114089 cites W1810797624 @default.
- W4225114089 cites W1963848568 @default.
- W4225114089 cites W1966210473 @default.
- W4225114089 cites W1969690844 @default.
- W4225114089 cites W1973666710 @default.
- W4225114089 cites W1976805974 @default.
- W4225114089 cites W1979490323 @default.
- W4225114089 cites W1983472709 @default.
- W4225114089 cites W1983664768 @default.
- W4225114089 cites W1993101448 @default.
- W4225114089 cites W1995744610 @default.
- W4225114089 cites W1997183854 @default.
- W4225114089 cites W2003326487 @default.
- W4225114089 cites W2004349171 @default.
- W4225114089 cites W2004465286 @default.
- W4225114089 cites W2007056945 @default.
- W4225114089 cites W2007127627 @default.
- W4225114089 cites W2008757142 @default.
- W4225114089 cites W2011197968 @default.
- W4225114089 cites W2013365571 @default.
- W4225114089 cites W2014929619 @default.
- W4225114089 cites W2015412261 @default.
- W4225114089 cites W2021490026 @default.
- W4225114089 cites W2024829972 @default.
- W4225114089 cites W2027496373 @default.
- W4225114089 cites W2028873942 @default.
- W4225114089 cites W2030479855 @default.
- W4225114089 cites W2033106089 @default.
- W4225114089 cites W2038245749 @default.
- W4225114089 cites W2042962261 @default.
- W4225114089 cites W2048117413 @default.
- W4225114089 cites W2051026238 @default.
- W4225114089 cites W2056466760 @default.
- W4225114089 cites W2064587984 @default.
- W4225114089 cites W2065021154 @default.
- W4225114089 cites W2065031087 @default.
- W4225114089 cites W2068417149 @default.
- W4225114089 cites W2076731990 @default.
- W4225114089 cites W2077358692 @default.
- W4225114089 cites W2088140877 @default.
- W4225114089 cites W2093083083 @default.
- W4225114089 cites W2100252473 @default.
- W4225114089 cites W2108089395 @default.
- W4225114089 cites W2112622836 @default.
- W4225114089 cites W2114216755 @default.
- W4225114089 cites W2132822330 @default.
- W4225114089 cites W2135247591 @default.
- W4225114089 cites W2152165298 @default.
- W4225114089 cites W2154945223 @default.
- W4225114089 cites W2155134319 @default.
- W4225114089 cites W2155706758 @default.
- W4225114089 cites W2157339124 @default.
- W4225114089 cites W2157408993 @default.
- W4225114089 cites W2157648426 @default.
- W4225114089 cites W2161763481 @default.
- W4225114089 cites W2163179762 @default.
- W4225114089 cites W2167382116 @default.
- W4225114089 cites W2168465208 @default.
- W4225114089 cites W2169329611 @default.
- W4225114089 cites W2180696344 @default.
- W4225114089 cites W2209442085 @default.
- W4225114089 cites W2313741435 @default.
- W4225114089 cites W2396189615 @default.
- W4225114089 cites W2398950401 @default.
- W4225114089 cites W2417911290 @default.
- W4225114089 cites W2484914234 @default.
- W4225114089 cites W2516322149 @default.
- W4225114089 cites W2525130569 @default.
- W4225114089 cites W2585546636 @default.
- W4225114089 cites W2586275499 @default.
- W4225114089 cites W2589764628 @default.
- W4225114089 cites W2590181299 @default.
- W4225114089 cites W2590268133 @default.
- W4225114089 cites W2600533839 @default.
- W4225114089 cites W2608611322 @default.
- W4225114089 cites W2611397450 @default.
- W4225114089 cites W2611663512 @default.
- W4225114089 cites W2614621771 @default.
- W4225114089 cites W2627086430 @default.
- W4225114089 cites W2648604848 @default.
- W4225114089 cites W2735383739 @default.
- W4225114089 cites W2736769485 @default.
- W4225114089 cites W2739292292 @default.