Matches in SemOpenAlex for { <https://semopenalex.org/work/W4247666721> ?p ?o ?g. }
- W4247666721 endingPage "812" @default.
- W4247666721 startingPage "783" @default.
- W4247666721 abstract "Fueled by ever-growing DNA sequence information, proteomics-the large scale analysis of proteins-has become one of the most important disciplines for characterizing gene function, for building functional linkages between protein molecules, and for providing insight into the mechanisms of biological processes in a high-throughput mode. It is now possible to examine the expression of more than 1000 proteins using mass spectrometry technology coupled with various separation methods. High-throughput yeast two-hybrid approaches and analysis of protein complexes using affinity tag purification have yielded valuable protein-protein interaction maps. Large-scale protein tagging and subcellular localization projects have provided considerable information about protein function. Finally, recent developments in protein microarray technology provide a versatile tool to study protein-protein, protein-nucleic acid, protein-lipid, enzyme-substrate, and protein-drug interactions. Other types of microarrays, though not fully developed, also show great potential in diagnostics, protein profiling, and drug identification and validation. This review discusses high-throughput technologies for proteome analysis and their applications. Also discussed are the approaches used for the integrated analysis of the voluminous sets of data generated by proteome analysis conducted on a global scale." @default.
- W4247666721 created "2022-05-12" @default.
- W4247666721 creator A5033955453 @default.
- W4247666721 creator A5050679690 @default.
- W4247666721 creator A5087724111 @default.
- W4247666721 date "2003-06-01" @default.
- W4247666721 modified "2023-10-14" @default.
- W4247666721 title "Proteomics" @default.
- W4247666721 cites W1485971068 @default.
- W4247666721 cites W1486817521 @default.
- W4247666721 cites W1486970791 @default.
- W4247666721 cites W1520738779 @default.
- W4247666721 cites W1543099628 @default.
- W4247666721 cites W1555106203 @default.
- W4247666721 cites W1562297375 @default.
- W4247666721 cites W1597678601 @default.
- W4247666721 cites W1658092509 @default.
- W4247666721 cites W1797925867 @default.
- W4247666721 cites W1918211917 @default.
- W4247666721 cites W1973255314 @default.
- W4247666721 cites W1973270679 @default.
- W4247666721 cites W1981627370 @default.
- W4247666721 cites W1986124354 @default.
- W4247666721 cites W1988287443 @default.
- W4247666721 cites W1990142733 @default.
- W4247666721 cites W1991661839 @default.
- W4247666721 cites W1992421514 @default.
- W4247666721 cites W1996693787 @default.
- W4247666721 cites W1999234724 @default.
- W4247666721 cites W2002255746 @default.
- W4247666721 cites W2002844202 @default.
- W4247666721 cites W2004704197 @default.
- W4247666721 cites W2005466661 @default.
- W4247666721 cites W2011246191 @default.
- W4247666721 cites W2012338624 @default.
- W4247666721 cites W2013410321 @default.
- W4247666721 cites W2015447457 @default.
- W4247666721 cites W2016493311 @default.
- W4247666721 cites W2017520863 @default.
- W4247666721 cites W2021990196 @default.
- W4247666721 cites W2022024802 @default.
- W4247666721 cites W2022576948 @default.
- W4247666721 cites W2023269042 @default.
- W4247666721 cites W2024797223 @default.
- W4247666721 cites W2025999411 @default.
- W4247666721 cites W2030157681 @default.
- W4247666721 cites W2037036397 @default.
- W4247666721 cites W2040711070 @default.
- W4247666721 cites W2040941311 @default.
- W4247666721 cites W2041887649 @default.
- W4247666721 cites W2046813978 @default.
- W4247666721 cites W2060145168 @default.
- W4247666721 cites W2061439657 @default.
- W4247666721 cites W2065304353 @default.
- W4247666721 cites W2071961611 @default.
- W4247666721 cites W2074033835 @default.
- W4247666721 cites W2074777027 @default.
- W4247666721 cites W2075122404 @default.
- W4247666721 cites W2079818352 @default.
- W4247666721 cites W2081617218 @default.
- W4247666721 cites W2082796552 @default.
- W4247666721 cites W2083453910 @default.
- W4247666721 cites W2084619201 @default.
- W4247666721 cites W2085401633 @default.
- W4247666721 cites W2090816585 @default.
- W4247666721 cites W2092032573 @default.
- W4247666721 cites W2096211374 @default.
- W4247666721 cites W2101327327 @default.
- W4247666721 cites W2110132014 @default.
- W4247666721 cites W2110438893 @default.
- W4247666721 cites W2111208057 @default.
- W4247666721 cites W2111668132 @default.
- W4247666721 cites W2113654464 @default.
- W4247666721 cites W2114724490 @default.
- W4247666721 cites W2118103468 @default.
- W4247666721 cites W2118177631 @default.
- W4247666721 cites W2121568234 @default.
- W4247666721 cites W2127775429 @default.
- W4247666721 cites W2132582966 @default.
- W4247666721 cites W2137335580 @default.
- W4247666721 cites W2140236864 @default.
- W4247666721 cites W2145787141 @default.
- W4247666721 cites W2146264532 @default.
- W4247666721 cites W2148984584 @default.
- W4247666721 cites W2149198894 @default.
- W4247666721 cites W2151832293 @default.
- W4247666721 cites W2152961480 @default.
- W4247666721 cites W2155432019 @default.
- W4247666721 cites W2157058776 @default.
- W4247666721 cites W2157523980 @default.
- W4247666721 cites W2159193014 @default.
- W4247666721 cites W2159265289 @default.
- W4247666721 cites W2160013892 @default.
- W4247666721 cites W2161574105 @default.
- W4247666721 cites W2165696748 @default.
- W4247666721 cites W2167869241 @default.
- W4247666721 cites W2168846334 @default.
- W4247666721 cites W2170652857 @default.