Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281477560> ?p ?o ?g. }
- W4281477560 endingPage "777.e2" @default.
- W4281477560 startingPage "769" @default.
- W4281477560 abstract "Age ≥80 years is known to be an independent risk factor for periprocedural stroke after transfemoral carotid artery stenting (TF-CAS) but not after carotid endarterectomy (CEA). The objective of the present study was to compare the perioperative outcomes for CEA, TF-CAS, and transcarotid artery revascularization (TCAR) among octogenarian patients (aged ≥80 years) overall and stratified by symptom status and degree of stenosis.All patients aged ≥80 years with 50% to 99% carotid artery stenosis who had undergone CEA, TF-CAS, or TCAR in the Vascular Quality Initiative (2005-2020) were included. We compared the perioperative (30-day) incidence of ipsilateral stroke or death for CEA vs TF-CAS vs TCAR using analysis of variance and multivariable logistic regression models. The results were confirmed in a sensitivity analysis stratified by symptom status and degree of stenosis.Overall, 28,571 carotid revascularization procedures were performed in patients aged ≥80 years: CEA, n = 20,912 (73.2%), TF-CAS, n = 3628 (12.7%), and TCAR, n = 4031 (14.1%). The median age was 83 years (interquartile range, 81.0-86.0 years); 49.8% of the patients were symptomatic (51.9% CEA, 46.2% TF-CAS, 42.4% TCAR); and 60.7% had high-grade stenosis (59.0% CEA, 65.2% TF-CAS, 65.4% TCAR). Perioperative stroke/death occurred most frequently following TF-CAS (6.6%), followed by TCAR (3.1%) and CEA (2.5%; P < .001). After adjusting for baseline differences between groups, the odds ratio (OR) for stroke/death was greater for TF-CAS vs CEA (adjusted OR [aOR], 3.35; 95% confidence interval [CI], 2.65-4.23), followed by TCAR vs CEA (aOR 1.49, 95% CI 1.18-1.87). The risk of perioperative stroke/death remained significantly greater for TF-CAS compared with CEA regardless of symptom status and degree of stenosis (P < .05 for all). In contrast, the risk of stroke/death was higher for TCAR vs CEA for asymptomatic patients (aOR, 2.04; 95% CI, 1.41-2.94) and those with high-grade stenosis (aOR, 1.49; 95% CI, 1.11-2.05) but similar for patients with symptomatic and moderate-grade disease (P > .05 for both). The risk of myocardial infarction was lower with TCAR (aOR, 0.59; 95% CI, 0.40-0.87) and TF-CAS (aOR, 0.56; 95% CI, 0.40-0.87) compared with CEA overall.Overall, TCAR and CEA can be safely offered to older adults, in particular, symptomatic patients and those with moderate-grade stenosis. TF-CAS should be avoided in older patients when possible." @default.
- W4281477560 created "2022-05-26" @default.
- W4281477560 creator A5000605336 @default.
- W4281477560 creator A5002297725 @default.
- W4281477560 creator A5017306144 @default.
- W4281477560 creator A5028214996 @default.
- W4281477560 creator A5035312566 @default.
- W4281477560 creator A5068598953 @default.
- W4281477560 creator A5071018251 @default.
- W4281477560 date "2022-09-01" @default.
- W4281477560 modified "2023-09-28" @default.
- W4281477560 title "Association of carotid revascularization approach with perioperative outcomes based on symptom status and degree of stenosis among octogenarians" @default.
- W4281477560 cites W1861317230 @default.
- W4281477560 cites W1965652425 @default.
- W4281477560 cites W2019465816 @default.
- W4281477560 cites W2021994086 @default.
- W4281477560 cites W2026786778 @default.
- W4281477560 cites W2036301547 @default.
- W4281477560 cites W2038169486 @default.
- W4281477560 cites W2067580608 @default.
- W4281477560 cites W2094030464 @default.
- W4281477560 cites W2140387021 @default.
- W4281477560 cites W2180989917 @default.
- W4281477560 cites W2225721238 @default.
- W4281477560 cites W2262327953 @default.
- W4281477560 cites W2418430490 @default.
- W4281477560 cites W2464520406 @default.
- W4281477560 cites W2592760528 @default.
- W4281477560 cites W2736330489 @default.
- W4281477560 cites W2783065741 @default.
- W4281477560 cites W2803383613 @default.
- W4281477560 cites W2804860811 @default.
- W4281477560 cites W2937436273 @default.
- W4281477560 cites W3004906809 @default.
- W4281477560 cites W3032904475 @default.
- W4281477560 cites W3077866375 @default.
- W4281477560 cites W3081511797 @default.
- W4281477560 cites W3108548390 @default.
- W4281477560 cites W3173746046 @default.
- W4281477560 cites W4244117401 @default.
- W4281477560 cites W4324264875 @default.
- W4281477560 cites W4376848366 @default.
- W4281477560 cites W2998961628 @default.
- W4281477560 doi "https://doi.org/10.1016/j.jvs.2022.04.027" @default.
- W4281477560 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35643202" @default.
- W4281477560 hasPublicationYear "2022" @default.
- W4281477560 type Work @default.
- W4281477560 citedByCount "5" @default.
- W4281477560 countsByYear W42814775602022 @default.
- W4281477560 countsByYear W42814775602023 @default.
- W4281477560 crossrefType "journal-article" @default.
- W4281477560 hasAuthorship W4281477560A5000605336 @default.
- W4281477560 hasAuthorship W4281477560A5002297725 @default.
- W4281477560 hasAuthorship W4281477560A5017306144 @default.
- W4281477560 hasAuthorship W4281477560A5028214996 @default.
- W4281477560 hasAuthorship W4281477560A5035312566 @default.
- W4281477560 hasAuthorship W4281477560A5068598953 @default.
- W4281477560 hasAuthorship W4281477560A5071018251 @default.
- W4281477560 hasConcept C119060515 @default.
- W4281477560 hasConcept C126322002 @default.
- W4281477560 hasConcept C127413603 @default.
- W4281477560 hasConcept C141071460 @default.
- W4281477560 hasConcept C156957248 @default.
- W4281477560 hasConcept C164705383 @default.
- W4281477560 hasConcept C2779464278 @default.
- W4281477560 hasConcept C2780007028 @default.
- W4281477560 hasConcept C2780645631 @default.
- W4281477560 hasConcept C2781068581 @default.
- W4281477560 hasConcept C31174226 @default.
- W4281477560 hasConcept C500558357 @default.
- W4281477560 hasConcept C71924100 @default.
- W4281477560 hasConcept C78519656 @default.
- W4281477560 hasConceptScore W4281477560C119060515 @default.
- W4281477560 hasConceptScore W4281477560C126322002 @default.
- W4281477560 hasConceptScore W4281477560C127413603 @default.
- W4281477560 hasConceptScore W4281477560C141071460 @default.
- W4281477560 hasConceptScore W4281477560C156957248 @default.
- W4281477560 hasConceptScore W4281477560C164705383 @default.
- W4281477560 hasConceptScore W4281477560C2779464278 @default.
- W4281477560 hasConceptScore W4281477560C2780007028 @default.
- W4281477560 hasConceptScore W4281477560C2780645631 @default.
- W4281477560 hasConceptScore W4281477560C2781068581 @default.
- W4281477560 hasConceptScore W4281477560C31174226 @default.
- W4281477560 hasConceptScore W4281477560C500558357 @default.
- W4281477560 hasConceptScore W4281477560C71924100 @default.
- W4281477560 hasConceptScore W4281477560C78519656 @default.
- W4281477560 hasFunder F4320332161 @default.
- W4281477560 hasFunder F4320337357 @default.
- W4281477560 hasIssue "3" @default.
- W4281477560 hasLocation W42814775601 @default.
- W4281477560 hasLocation W42814775602 @default.
- W4281477560 hasOpenAccess W4281477560 @default.
- W4281477560 hasPrimaryLocation W42814775601 @default.
- W4281477560 hasRelatedWork W1986987068 @default.
- W4281477560 hasRelatedWork W2036253422 @default.
- W4281477560 hasRelatedWork W2058586059 @default.
- W4281477560 hasRelatedWork W2299824099 @default.
- W4281477560 hasRelatedWork W2318928928 @default.