Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285993015> ?p ?o ?g. }
- W4285993015 endingPage "958" @default.
- W4285993015 startingPage "942" @default.
- W4285993015 abstract "The 3D printed porous titanium alloy scaffolds are beneficial to enhance angiogenesis, osteoblast adhesion, and promote osseointegration. However, titanium alloys are biologically inert, which makes the bond between the implant and bone tissue weak and prone to loosening. Inspired by the natural biological marine mussels, we designed four-claw-shaped mussel-derived bioactive peptides for the decoration of porous titanium alloy scaffolds: adhesion peptide-DOPA, anchoring peptide-RGD and osteogenic-inducing peptide-BMP-2. And the bifunctionalization of 3D-printed porous titanium alloy scaffolds was evaluated in vivo in a rabbit model of bone defect with excellent promotion of osseointegration and mechanical stability. Our results show that the in vivo osseointegration ability of the modified 3D printed porous titanium alloy test piece is significantly improved, and the bifunctional polypeptide coating group E has the strongest osseointegration ability. In conclusion, our experimental design partially solves the problems of stress shielding effect and biological inertness, and provides a convenient and feasible method for the clinical application of titanium alloy implants in biomedical implant materials." @default.
- W4285993015 created "2022-07-21" @default.
- W4285993015 creator A5000005088 @default.
- W4285993015 creator A5020419888 @default.
- W4285993015 creator A5024635379 @default.
- W4285993015 creator A5025978291 @default.
- W4285993015 creator A5030884401 @default.
- W4285993015 creator A5038636585 @default.
- W4285993015 creator A5042775341 @default.
- W4285993015 date "2022-07-20" @default.
- W4285993015 modified "2023-10-18" @default.
- W4285993015 title "In vivo study of dual functionalized mussel-derived bioactive peptides promoting 3D-printed porous Ti6Al4V scaffolds for repair of rabbit femoral defects" @default.
- W4285993015 cites W1983399188 @default.
- W4285993015 cites W1985545724 @default.
- W4285993015 cites W1986138379 @default.
- W4285993015 cites W1989079701 @default.
- W4285993015 cites W2014446239 @default.
- W4285993015 cites W2017033521 @default.
- W4285993015 cites W2025975038 @default.
- W4285993015 cites W2031294040 @default.
- W4285993015 cites W2042261220 @default.
- W4285993015 cites W2043992317 @default.
- W4285993015 cites W2063082021 @default.
- W4285993015 cites W2074645659 @default.
- W4285993015 cites W2079268771 @default.
- W4285993015 cites W2080790182 @default.
- W4285993015 cites W2081965734 @default.
- W4285993015 cites W2082783879 @default.
- W4285993015 cites W2097028187 @default.
- W4285993015 cites W2110610796 @default.
- W4285993015 cites W2117969726 @default.
- W4285993015 cites W2129012148 @default.
- W4285993015 cites W2261324366 @default.
- W4285993015 cites W2299773887 @default.
- W4285993015 cites W2460671768 @default.
- W4285993015 cites W2462313234 @default.
- W4285993015 cites W2514771391 @default.
- W4285993015 cites W2536181379 @default.
- W4285993015 cites W2661199540 @default.
- W4285993015 cites W2754790651 @default.
- W4285993015 cites W2757064281 @default.
- W4285993015 cites W2791619823 @default.
- W4285993015 cites W2800988732 @default.
- W4285993015 cites W2801120328 @default.
- W4285993015 cites W2803850251 @default.
- W4285993015 cites W2809667977 @default.
- W4285993015 cites W2845197751 @default.
- W4285993015 cites W2902609311 @default.
- W4285993015 cites W2946520575 @default.
- W4285993015 cites W2961599656 @default.
- W4285993015 cites W2989318902 @default.
- W4285993015 cites W2996613942 @default.
- W4285993015 cites W3015884054 @default.
- W4285993015 cites W3024211393 @default.
- W4285993015 cites W3024646272 @default.
- W4285993015 cites W3058000131 @default.
- W4285993015 cites W3085579791 @default.
- W4285993015 cites W3092124990 @default.
- W4285993015 cites W3124159137 @default.
- W4285993015 cites W3124387385 @default.
- W4285993015 cites W3139377635 @default.
- W4285993015 cites W3145929282 @default.
- W4285993015 cites W3200123275 @default.
- W4285993015 cites W4200107503 @default.
- W4285993015 cites W4200440853 @default.
- W4285993015 doi "https://doi.org/10.1177/08853282221117209" @default.
- W4285993015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35856165" @default.
- W4285993015 hasPublicationYear "2022" @default.
- W4285993015 type Work @default.
- W4285993015 citedByCount "3" @default.
- W4285993015 countsByYear W42859930152023 @default.
- W4285993015 crossrefType "journal-article" @default.
- W4285993015 hasAuthorship W4285993015A5000005088 @default.
- W4285993015 hasAuthorship W4285993015A5020419888 @default.
- W4285993015 hasAuthorship W4285993015A5024635379 @default.
- W4285993015 hasAuthorship W4285993015A5025978291 @default.
- W4285993015 hasAuthorship W4285993015A5030884401 @default.
- W4285993015 hasAuthorship W4285993015A5038636585 @default.
- W4285993015 hasAuthorship W4285993015A5042775341 @default.
- W4285993015 hasConcept C101414908 @default.
- W4285993015 hasConcept C136229726 @default.
- W4285993015 hasConcept C141071460 @default.
- W4285993015 hasConcept C150903083 @default.
- W4285993015 hasConcept C159985019 @default.
- W4285993015 hasConcept C191897082 @default.
- W4285993015 hasConcept C192562407 @default.
- W4285993015 hasConcept C207001950 @default.
- W4285993015 hasConcept C2778985418 @default.
- W4285993015 hasConcept C2780026712 @default.
- W4285993015 hasConcept C2781411149 @default.
- W4285993015 hasConcept C506065880 @default.
- W4285993015 hasConcept C71924100 @default.
- W4285993015 hasConcept C84416704 @default.
- W4285993015 hasConcept C86803240 @default.
- W4285993015 hasConcept C8953137 @default.
- W4285993015 hasConceptScore W4285993015C101414908 @default.
- W4285993015 hasConceptScore W4285993015C136229726 @default.
- W4285993015 hasConceptScore W4285993015C141071460 @default.