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• W4288045802 endingPage "132416" @default.
• W4288045802 startingPage "132416" @default.
• W4288045802 abstract "Recently, cervical cancer seriously threatens women’s health and life, where squamous cell carcinoma antigen (SCCA) is a representative biomarker widely applied for the early diagnosis and therapy. Herein, bimetallic PtFe alloyed nanoparticles were efficiently decorated on three-dimensional hollow N-doped carbon nanoflowers (PtFe/H-NCFs) by a simple pyrolysis strategy. We strictly investigated the influences of the hollow nanoflower-like structure, N-doping and highly active PtFe nanoalloys on the detection signals from Fe(CN) 6 3– oxidation, coupled with their effects on the loading of the SCCA antibody. Consequently, a high-performance label-free PtFe/H-NCFs-based biosensor was established for ultrasensitive analysis of SCCA, with a wider linear range of 0.01 pg mL –1 -10 ng mL –1 and a lower limit of detection (0.003 pg mL –1 , S/N = 3). The developed sensor holds potential applications for monitoring biomarkers in early diagnosis and clinic therapy. • PtFe/H-NCFs with large surface area were prepared by a one-pot pyrolysis strategy. • PtFe nanoparticles were well decorated on the 3D H-NCFs, showing high electrocatalytic activity. • The prepared immunosensor showed highly improved analytical performance for detecting SCCA." @default.
• W4288045802 created "2022-07-27" @default.
• W4288045802 creator A5026610143 @default.
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• W4288045802 date "2022-11-01" @default.
• W4288045802 modified "2023-10-04" @default.
• W4288045802 title "Bimetallic PtFe alloyed nanoparticles decorated on 3D hollow N-doped carbon nanoflowers as efficient electrochemical biosensing interfaces for ultrasensitive detection of SCCA" @default.
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• W4288045802 doi "https://doi.org/10.1016/j.snb.2022.132416" @default.
• W4288045802 hasPublicationYear "2022" @default.
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