Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297613908> ?p ?o ?g. }
- W4297613908 endingPage "1503" @default.
- W4297613908 startingPage "1497" @default.
- W4297613908 abstract "Visualizing the spatial distribution of chemical compositions in biological tissues is of great importance to study fundamental biological processes and origin of diseases. Raman microscopy, one of the label-free vibrational imaging techniques, has been employed for chemical characterization of tissues. However, the low sensitivity of Raman spectroscopy often requires a long acquisition time of Raman measurement or a high laser power, or both, which prevents one from investigating large-area tissues in a nondestructive manner. In this work, we demonstrated chemical imaging of heart tissues using mid-infrared photothermal (MIP) microscopy that simultaneously achieves the high sensitivity benefited from IR absorption of molecules and the high spatial resolution down to a few micrometers. We successfully visualized the distributions of different biomolecules, including proteins, phosphate-including proteins, and lipids/carbohydrates/amino acids. Further, we experimentally compared MIP microscopy with Raman microscopy to evaluate the sensitivity and photodamage to tissues. We proved that MIP microscopy is a highly sensitive technique for obtaining vibrational information of molecules in a broad fingerprint region, thereby it could be employed for biological and diagnostic applications, such as live-tissue imaging." @default.
- W4297613908 created "2022-09-30" @default.
- W4297613908 creator A5013765552 @default.
- W4297613908 creator A5050010503 @default.
- W4297613908 creator A5056258680 @default.
- W4297613908 creator A5082436433 @default.
- W4297613908 date "2022-09-07" @default.
- W4297613908 modified "2023-10-17" @default.
- W4297613908 title "High-sensitivity hyperspectral vibrational imaging of heart tissues by mid-infrared photothermal microscopy" @default.
- W4297613908 cites W1544866754 @default.
- W4297613908 cites W1564394441 @default.
- W4297613908 cites W1965558299 @default.
- W4297613908 cites W1989619445 @default.
- W4297613908 cites W1995373608 @default.
- W4297613908 cites W2002257633 @default.
- W4297613908 cites W2009813088 @default.
- W4297613908 cites W2016994104 @default.
- W4297613908 cites W2020170071 @default.
- W4297613908 cites W2022675211 @default.
- W4297613908 cites W2050786163 @default.
- W4297613908 cites W2068991920 @default.
- W4297613908 cites W2092122026 @default.
- W4297613908 cites W2208325535 @default.
- W4297613908 cites W2568381409 @default.
- W4297613908 cites W2738334925 @default.
- W4297613908 cites W2776866580 @default.
- W4297613908 cites W2806467006 @default.
- W4297613908 cites W2806722297 @default.
- W4297613908 cites W2890141567 @default.
- W4297613908 cites W2895261396 @default.
- W4297613908 cites W2916749991 @default.
- W4297613908 cites W2962001627 @default.
- W4297613908 cites W2964001913 @default.
- W4297613908 cites W2964108977 @default.
- W4297613908 cites W2990639468 @default.
- W4297613908 cites W3003530847 @default.
- W4297613908 cites W3037115872 @default.
- W4297613908 cites W3093728023 @default.
- W4297613908 cites W3097197014 @default.
- W4297613908 cites W3113197270 @default.
- W4297613908 cites W3119774682 @default.
- W4297613908 cites W3127349861 @default.
- W4297613908 cites W3133454886 @default.
- W4297613908 cites W4200355844 @default.
- W4297613908 cites W4214827333 @default.
- W4297613908 cites W4221107068 @default.
- W4297613908 doi "https://doi.org/10.1007/s44211-022-00182-8" @default.
- W4297613908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36070070" @default.
- W4297613908 hasPublicationYear "2022" @default.
- W4297613908 type Work @default.
- W4297613908 citedByCount "3" @default.
- W4297613908 countsByYear W42976139082023 @default.
- W4297613908 crossrefType "journal-article" @default.
- W4297613908 hasAuthorship W4297613908A5013765552 @default.
- W4297613908 hasAuthorship W4297613908A5050010503 @default.
- W4297613908 hasAuthorship W4297613908A5056258680 @default.
- W4297613908 hasAuthorship W4297613908A5082436433 @default.
- W4297613908 hasBestOaLocation W42976139081 @default.
- W4297613908 hasConcept C120665830 @default.
- W4297613908 hasConcept C121332964 @default.
- W4297613908 hasConcept C127313418 @default.
- W4297613908 hasConcept C147080431 @default.
- W4297613908 hasConcept C158355884 @default.
- W4297613908 hasConcept C159078339 @default.
- W4297613908 hasConcept C171250308 @default.
- W4297613908 hasConcept C182606246 @default.
- W4297613908 hasConcept C185592680 @default.
- W4297613908 hasConcept C192562407 @default.
- W4297613908 hasConcept C2987860518 @default.
- W4297613908 hasConcept C40003534 @default.
- W4297613908 hasConcept C49853544 @default.
- W4297613908 hasConcept C55493867 @default.
- W4297613908 hasConcept C62649853 @default.
- W4297613908 hasConcept C65597285 @default.
- W4297613908 hasConceptScore W4297613908C120665830 @default.
- W4297613908 hasConceptScore W4297613908C121332964 @default.
- W4297613908 hasConceptScore W4297613908C127313418 @default.
- W4297613908 hasConceptScore W4297613908C147080431 @default.
- W4297613908 hasConceptScore W4297613908C158355884 @default.
- W4297613908 hasConceptScore W4297613908C159078339 @default.
- W4297613908 hasConceptScore W4297613908C171250308 @default.
- W4297613908 hasConceptScore W4297613908C182606246 @default.
- W4297613908 hasConceptScore W4297613908C185592680 @default.
- W4297613908 hasConceptScore W4297613908C192562407 @default.
- W4297613908 hasConceptScore W4297613908C2987860518 @default.
- W4297613908 hasConceptScore W4297613908C40003534 @default.
- W4297613908 hasConceptScore W4297613908C49853544 @default.
- W4297613908 hasConceptScore W4297613908C55493867 @default.
- W4297613908 hasConceptScore W4297613908C62649853 @default.
- W4297613908 hasConceptScore W4297613908C65597285 @default.
- W4297613908 hasIssue "12" @default.
- W4297613908 hasLocation W42976139081 @default.
- W4297613908 hasLocation W42976139082 @default.
- W4297613908 hasOpenAccess W4297613908 @default.
- W4297613908 hasPrimaryLocation W42976139081 @default.
- W4297613908 hasRelatedWork W163927463 @default.
- W4297613908 hasRelatedWork W1993874650 @default.
- W4297613908 hasRelatedWork W2027399350 @default.