Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310857030> ?p ?o ?g. }
- W4310857030 endingPage "101208" @default.
- W4310857030 startingPage "101208" @default.
- W4310857030 abstract "It is now well established that vitamins D, E, and K and carotenoids are not absorbed solely through passive diffusion. Broad-specificity membrane transporters such as SR-BI (scavenger receptor class B type I), CD36 (CD36 molecule), NPC1L1 (Niemann Pick C1-like 1) or ABCA1 (ATP-binding cassette A1) are involved in the uptake of these micronutrients from the lumen to the enterocyte cytosol and in their secretion into the bloodstream. Recently, the existence of efflux pathways from the enterocyte back to the lumen or from the bloodstream to the lumen, involving ABCB1 (P-glycoprotein/MDR1) or the ABCG5/ABCG8 complex, has also been evidenced for vitamins D and K. Surprisingly, no membrane proteins have been involved in dietary vitamin A uptake so far. After an overview of the metabolism of fat-soluble vitamins and carotenoids along the gastrointestinal tract (from the mouth to the colon where interactions with microbiota may occur), a focus is placed on the identified and candidate proteins participating in the apical uptake, intracellular transport, basolateral secretion and efflux back to the lumen of fat-soluble vitamins and carotenoids in enterocytes. This review also highlights the mechanisms that remain to be identified to fully unravel the pathways involved in fat-soluble vitamin and carotenoid intestinal absorption." @default.
- W4310857030 created "2022-12-19" @default.
- W4310857030 creator A5026981598 @default.
- W4310857030 date "2023-01-01" @default.
- W4310857030 modified "2023-10-16" @default.
- W4310857030 title "Proteins involved in fat-soluble vitamin and carotenoid transport across the intestinal cells: New insights from the past decade" @default.
- W4310857030 cites W1575771007 @default.
- W4310857030 cites W1762001276 @default.
- W4310857030 cites W1835526604 @default.
- W4310857030 cites W1876428681 @default.
- W4310857030 cites W1896983858 @default.
- W4310857030 cites W1907963035 @default.
- W4310857030 cites W1908587496 @default.
- W4310857030 cites W1914937380 @default.
- W4310857030 cites W1917316869 @default.
- W4310857030 cites W1922389415 @default.
- W4310857030 cites W1928861100 @default.
- W4310857030 cites W1945543976 @default.
- W4310857030 cites W1948121113 @default.
- W4310857030 cites W1958191918 @default.
- W4310857030 cites W1964821386 @default.
- W4310857030 cites W1964890275 @default.
- W4310857030 cites W1965937044 @default.
- W4310857030 cites W1968826659 @default.
- W4310857030 cites W1972947190 @default.
- W4310857030 cites W1976138674 @default.
- W4310857030 cites W1976521385 @default.
- W4310857030 cites W1979471324 @default.
- W4310857030 cites W1980511079 @default.
- W4310857030 cites W1983270609 @default.
- W4310857030 cites W1985413280 @default.
- W4310857030 cites W1985526660 @default.
- W4310857030 cites W1985923430 @default.
- W4310857030 cites W1986881140 @default.
- W4310857030 cites W1991274568 @default.
- W4310857030 cites W1994348363 @default.
- W4310857030 cites W1994454511 @default.
- W4310857030 cites W1994631943 @default.
- W4310857030 cites W1995822935 @default.
- W4310857030 cites W1999132350 @default.
- W4310857030 cites W2001901796 @default.
- W4310857030 cites W2003646122 @default.
- W4310857030 cites W2009478798 @default.
- W4310857030 cites W2011498151 @default.
- W4310857030 cites W2013307146 @default.
- W4310857030 cites W2022054395 @default.
- W4310857030 cites W2022373508 @default.
- W4310857030 cites W2025338322 @default.
- W4310857030 cites W2026636091 @default.
- W4310857030 cites W2027590118 @default.
- W4310857030 cites W2030607230 @default.
- W4310857030 cites W2032019797 @default.
- W4310857030 cites W2033728999 @default.
- W4310857030 cites W2035248522 @default.
- W4310857030 cites W2035448353 @default.
- W4310857030 cites W2037147303 @default.
- W4310857030 cites W2040853816 @default.
- W4310857030 cites W2041767949 @default.
- W4310857030 cites W2045070363 @default.
- W4310857030 cites W2045301052 @default.
- W4310857030 cites W2045396633 @default.
- W4310857030 cites W2045463616 @default.
- W4310857030 cites W2045660497 @default.
- W4310857030 cites W2048576901 @default.
- W4310857030 cites W2048919784 @default.
- W4310857030 cites W2052011436 @default.
- W4310857030 cites W2053633604 @default.
- W4310857030 cites W2059014306 @default.
- W4310857030 cites W2060140841 @default.
- W4310857030 cites W2062128881 @default.
- W4310857030 cites W2062582874 @default.
- W4310857030 cites W2066483255 @default.
- W4310857030 cites W2067145199 @default.
- W4310857030 cites W2073459028 @default.
- W4310857030 cites W2075301262 @default.
- W4310857030 cites W2075597895 @default.
- W4310857030 cites W2079272597 @default.
- W4310857030 cites W2079633519 @default.
- W4310857030 cites W2079923716 @default.
- W4310857030 cites W2082489663 @default.
- W4310857030 cites W2083332433 @default.
- W4310857030 cites W2083984345 @default.
- W4310857030 cites W2086933080 @default.
- W4310857030 cites W2087511261 @default.
- W4310857030 cites W2087807294 @default.
- W4310857030 cites W2093611015 @default.
- W4310857030 cites W2094873926 @default.
- W4310857030 cites W2094929865 @default.
- W4310857030 cites W2098626805 @default.
- W4310857030 cites W2098959116 @default.
- W4310857030 cites W2106554416 @default.
- W4310857030 cites W2108478956 @default.
- W4310857030 cites W2108732045 @default.
- W4310857030 cites W2111032891 @default.
- W4310857030 cites W2113803884 @default.
- W4310857030 cites W2113954046 @default.
- W4310857030 cites W2114713909 @default.
- W4310857030 cites W2116900736 @default.