Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328105355> ?p ?o ?g. }
- W4328105355 endingPage "60" @default.
- W4328105355 startingPage "53" @default.
- W4328105355 abstract "Strategies for improving the quality of oocytes have important theoretical and practical significance for increasing the efficiency of livestock breeding. In this respect, the accumulation of reactive oxygen species (ROS) is a major factor affecting the development of oocytes and embryos. This study investigated the effects of Dendrobium nobile extract (DNE) on the in vitro maturation of bovine oocytes and embryonic development after IVF. DNE is an extract from Dendrobium rhizomes that contains alkaloids with anti-inflammatory, anti-cancer and anti-ageing functions. Various concentrations of DNE (0, 5, 10, 20 and 50 μmol/L) were added during oocyte maturation in vitro, and we found that 10 μmol/L of DNE remarkably increased the oocyte maturation rate, the subsequent blastocyst formation rate and embryo quality. Further, we found that DNE treatment decreased the frequency of spindle/chromosome defects and ROS and increased the oocyte glutathione and mitochondrial membrane potential in oocytes. Moreover, DNE upregulated the expression of oxidative stress-related genes (Sirt1, Sirt2, Sirt3 and Sod1) in oocytes and apoptosis-related genes (Caspase-3, Caspase-4, Bax, Bcl-xl and Survivin) in blastocysts. These results suggest that DNE supplementation can promote oocyte maturation and subsequent embryonic development by regulating redox reactions and inhibiting embryonic apoptosis." @default.
- W4328105355 created "2023-03-22" @default.
- W4328105355 creator A5019957452 @default.
- W4328105355 creator A5028010176 @default.
- W4328105355 creator A5029871219 @default.
- W4328105355 creator A5063870450 @default.
- W4328105355 creator A5065254777 @default.
- W4328105355 creator A5067442824 @default.
- W4328105355 creator A5082558209 @default.
- W4328105355 creator A5087143306 @default.
- W4328105355 creator A5090567275 @default.
- W4328105355 date "2023-06-01" @default.
- W4328105355 modified "2023-10-16" @default.
- W4328105355 title "Dendrobine enhances bovine oocyte maturation and subsequent embryonic development and quality" @default.
- W4328105355 cites W1912200205 @default.
- W4328105355 cites W1970101659 @default.
- W4328105355 cites W1981905164 @default.
- W4328105355 cites W1994547407 @default.
- W4328105355 cites W2053605246 @default.
- W4328105355 cites W2402318285 @default.
- W4328105355 cites W2416584128 @default.
- W4328105355 cites W2508367806 @default.
- W4328105355 cites W2571030681 @default.
- W4328105355 cites W2574762612 @default.
- W4328105355 cites W2772777112 @default.
- W4328105355 cites W2805353014 @default.
- W4328105355 cites W2925395230 @default.
- W4328105355 cites W2944369609 @default.
- W4328105355 cites W2948811244 @default.
- W4328105355 cites W2968594401 @default.
- W4328105355 cites W2982294903 @default.
- W4328105355 cites W2992719125 @default.
- W4328105355 cites W2995820865 @default.
- W4328105355 cites W2999138658 @default.
- W4328105355 cites W3005070287 @default.
- W4328105355 cites W3091285247 @default.
- W4328105355 cites W3107793053 @default.
- W4328105355 cites W3108050475 @default.
- W4328105355 cites W3166116388 @default.
- W4328105355 cites W3176207652 @default.
- W4328105355 cites W3201325144 @default.
- W4328105355 cites W3212832767 @default.
- W4328105355 cites W3215942050 @default.
- W4328105355 cites W4281743795 @default.
- W4328105355 cites W4288080382 @default.
- W4328105355 cites W4296146232 @default.
- W4328105355 cites W4303685456 @default.
- W4328105355 doi "https://doi.org/10.1016/j.theriogenology.2023.03.015" @default.
- W4328105355 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36972665" @default.
- W4328105355 hasPublicationYear "2023" @default.
- W4328105355 type Work @default.
- W4328105355 citedByCount "1" @default.
- W4328105355 crossrefType "journal-article" @default.
- W4328105355 hasAuthorship W4328105355A5019957452 @default.
- W4328105355 hasAuthorship W4328105355A5028010176 @default.
- W4328105355 hasAuthorship W4328105355A5029871219 @default.
- W4328105355 hasAuthorship W4328105355A5063870450 @default.
- W4328105355 hasAuthorship W4328105355A5065254777 @default.
- W4328105355 hasAuthorship W4328105355A5067442824 @default.
- W4328105355 hasAuthorship W4328105355A5082558209 @default.
- W4328105355 hasAuthorship W4328105355A5087143306 @default.
- W4328105355 hasAuthorship W4328105355A5090567275 @default.
- W4328105355 hasConcept C104317684 @default.
- W4328105355 hasConcept C145103041 @default.
- W4328105355 hasConcept C16685009 @default.
- W4328105355 hasConcept C181199279 @default.
- W4328105355 hasConcept C185592680 @default.
- W4328105355 hasConcept C196843134 @default.
- W4328105355 hasConcept C2775838275 @default.
- W4328105355 hasConcept C2775966511 @default.
- W4328105355 hasConcept C2776108821 @default.
- W4328105355 hasConcept C2776151105 @default.
- W4328105355 hasConcept C2776690073 @default.
- W4328105355 hasConcept C2778177303 @default.
- W4328105355 hasConcept C48349386 @default.
- W4328105355 hasConcept C538909803 @default.
- W4328105355 hasConcept C54355233 @default.
- W4328105355 hasConcept C55493867 @default.
- W4328105355 hasConcept C71924100 @default.
- W4328105355 hasConcept C86803240 @default.
- W4328105355 hasConcept C87073359 @default.
- W4328105355 hasConcept C95444343 @default.
- W4328105355 hasConceptScore W4328105355C104317684 @default.
- W4328105355 hasConceptScore W4328105355C145103041 @default.
- W4328105355 hasConceptScore W4328105355C16685009 @default.
- W4328105355 hasConceptScore W4328105355C181199279 @default.
- W4328105355 hasConceptScore W4328105355C185592680 @default.
- W4328105355 hasConceptScore W4328105355C196843134 @default.
- W4328105355 hasConceptScore W4328105355C2775838275 @default.
- W4328105355 hasConceptScore W4328105355C2775966511 @default.
- W4328105355 hasConceptScore W4328105355C2776108821 @default.
- W4328105355 hasConceptScore W4328105355C2776151105 @default.
- W4328105355 hasConceptScore W4328105355C2776690073 @default.
- W4328105355 hasConceptScore W4328105355C2778177303 @default.
- W4328105355 hasConceptScore W4328105355C48349386 @default.
- W4328105355 hasConceptScore W4328105355C538909803 @default.
- W4328105355 hasConceptScore W4328105355C54355233 @default.
- W4328105355 hasConceptScore W4328105355C55493867 @default.