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• W4366990580 abstract "Older adults are at high-risk for a post-operative intensive care unit (ICU) admission, yet little is known about the impact of these admissions on quality of life. The objective of this study was to evaluate the impact of an unexpected post-operative ICU admission on the burden of cancer symptoms among older adults who underwent high-intensity cancer surgery and survived to hospital discharge.We performed a population-based cohort study of older adults (age ≥ 70) who underwent high-intensity cancer surgery and survived to hospital discharge in Ontario, Canada (2007-2017). Using the Edmonton Symptom Assessment System (ESAS), a standardized tool that quantifies patient-reported physical, mental, and emotional symptoms, we described the burden of cancer symptoms during the year after surgery. Total symptom scores ≥ 40 indicated a moderate-to-severe symptom burden. Modified log-Poisson analysis was used to estimate the impact of an unexpected post-operative ICU admission (admission not related to routine monitoring) on the likelihood of experiencing a moderate-to-severe symptom burden during the year after surgery, accounting for potential confounders. We then used multivariable generalized linear mixed models to model symptom trajectories among patients with two or more ESAS assessments. A 10-point difference in total symptom scores was considered clinically significant.Among 16,560 patients (mean age 76.5 years; 43.4% female), 1,503 (9.1%) had an unexpected ICU admission. After accounting for baseline characteristics, patients with an unexcepted ICU admission were more likely to experience a moderate-to-severe symptom burden relative to those without an unexpected ICU admission (RR 1.64, 95% CI 1.31-2.05). Specifically, among patients with an unexcepted ICU admission the average probability of experiencing moderate-to-severe symptoms ranged from 6.9% (95 CI 5.8-8.3%) during the first month after surgery to 3.2% (95% CI 0.9-11.7%) at the end of the year. Among the 11,229 (67.8%) patients with multiple ESAS assessments, adjusted differences in total scores between patients with and without an unexpected ICU admission ranged from 2.0 to 5.7-points throughout the year (p < 0.001).While unexpected ICU admissions are associated with a small increase in the likelihood of experiencing a moderate-to-severe symptom burden, most patients do not experience a high overall symptom burden during the year after surgery. These findings support the role of aggressive therapy among older adults after major surgery." @default.
• W4366990580 created "2023-04-27" @default.
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• W4366990580 date "2023-04-25" @default.
• W4366990580 modified "2023-10-17" @default.
• W4366990580 title "The impact of unexpected intensive care unit admission after cancer surgery on long-term symptom burden among older adults: a population-based longitudinal analysis" @default.
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• W4366990580 cites W1630831866 @default.
• W4366990580 cites W1768372171 @default.
• W4366990580 cites W1971679176 @default.
• W4366990580 cites W1974591550 @default.
• W4366990580 cites W1975371513 @default.
• W4366990580 cites W1977488532 @default.
• W4366990580 cites W1977733462 @default.
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• W4366990580 cites W2028702088 @default.
• W4366990580 cites W2029822285 @default.
• W4366990580 cites W2036314243 @default.
• W4366990580 cites W2042004458 @default.
• W4366990580 cites W2045588217 @default.
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• W4366990580 cites W2049491523 @default.
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• W4366990580 cites W2119050733 @default.
• W4366990580 cites W2121645853 @default.
• W4366990580 cites W2130845266 @default.
• W4366990580 cites W2136529928 @default.
• W4366990580 cites W2138695840 @default.
• W4366990580 cites W2144858320 @default.
• W4366990580 cites W2154221980 @default.
• W4366990580 cites W2203417047 @default.
• W4366990580 cites W2227283568 @default.
• W4366990580 cites W22429564 @default.
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• W4366990580 cites W2489062106 @default.
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• W4366990580 cites W2621090721 @default.
• W4366990580 cites W2792097174 @default.
• W4366990580 cites W2804920713 @default.
• W4366990580 cites W2809627097 @default.
• W4366990580 cites W2888723514 @default.
• W4366990580 cites W2901642582 @default.
• W4366990580 cites W2916745828 @default.
• W4366990580 cites W2946490383 @default.
• W4366990580 cites W2964702710 @default.
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• W4366990580 doi "https://doi.org/10.1186/s13054-023-04415-8" @default.
• W4366990580 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37098625" @default.
• W4366990580 hasPublicationYear "2023" @default.
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