Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366991083> ?p ?o ?g. }
- W4366991083 abstract "Significance, AimsThe neurovascular mechanisms underlying the initiation of absence seizures and their dynamics are still not well understood. The objective of this study was to better noninvasively characterize the dynamics of the neuronal and vascular network at the transition from the interictal state to the ictal state of absence seizures and back to the interictal state using a combined electroencephalography (EEG), functional near-infrared spectroscopy (fNIRS), and diffuse correlation spectroscopy (DCS) approach. The second objective was to develop hypotheses about the neuronal and vascular mechanisms that propel the networks to the 3-Hz spikes and wave discharges (SWDs) observed during absence seizures.ApproachesWe evaluated the simultaneous changes in electrical (neuronal) and optical dynamics [hemodynamic, with changes in (Hb) and cerebral blood flow] of 8 pediatric patients experiencing 25 typical childhood absence seizures during the transition from the interictal state to the absence seizure by simultaneously performing EEG, fNIRS, and DCS.ResultsStarting from ∼20 s before the onset of the SWD, we observed a transient direct current potential shift that correlated with alterations in functional fNIRS and DCS measurements of the cerebral hemodynamics detecting the preictal changes.DiscussionOur noninvasive multimodal approach highlights the dynamic interactions between the neuronal and vascular compartments that take place in the neuronal network near the time of the onset of absence seizures in a very specific cerebral hemodynamic environment. These noninvasive approaches contribute to a better understanding of the electrical hemodynamic environment prior to seizure onset. Whether this may ultimately be relevant for diagnostic and therapeutic approaches requires further evaluation." @default.
- W4366991083 created "2023-04-27" @default.
- W4366991083 creator A5055877889 @default.
- W4366991083 creator A5059258364 @default.
- W4366991083 creator A5077075512 @default.
- W4366991083 creator A5078995732 @default.
- W4366991083 date "2023-04-25" @default.
- W4366991083 modified "2023-10-18" @default.
- W4366991083 title "Preictal neuronal and vascular activity precedes the onset of childhood absence seizure: direct current potential shifts and their correlation with hemodynamic activity" @default.
- W4366991083 cites W1465406551 @default.
- W4366991083 cites W1487148446 @default.
- W4366991083 cites W1583209675 @default.
- W4366991083 cites W166505227 @default.
- W4366991083 cites W1887676264 @default.
- W4366991083 cites W1947035503 @default.
- W4366991083 cites W1964274406 @default.
- W4366991083 cites W1965799839 @default.
- W4366991083 cites W1969182318 @default.
- W4366991083 cites W1972032416 @default.
- W4366991083 cites W1974316717 @default.
- W4366991083 cites W1974347565 @default.
- W4366991083 cites W1977813492 @default.
- W4366991083 cites W1979635428 @default.
- W4366991083 cites W1979819271 @default.
- W4366991083 cites W1980508513 @default.
- W4366991083 cites W1981140845 @default.
- W4366991083 cites W1983539811 @default.
- W4366991083 cites W1986495756 @default.
- W4366991083 cites W1993627760 @default.
- W4366991083 cites W1998055357 @default.
- W4366991083 cites W2003739479 @default.
- W4366991083 cites W2004685246 @default.
- W4366991083 cites W2013712141 @default.
- W4366991083 cites W2015068799 @default.
- W4366991083 cites W2016371147 @default.
- W4366991083 cites W2019774050 @default.
- W4366991083 cites W2020504534 @default.
- W4366991083 cites W2021841799 @default.
- W4366991083 cites W2023360305 @default.
- W4366991083 cites W2025059256 @default.
- W4366991083 cites W2026154459 @default.
- W4366991083 cites W2028216578 @default.
- W4366991083 cites W2033448026 @default.
- W4366991083 cites W2033564918 @default.
- W4366991083 cites W2035252615 @default.
- W4366991083 cites W2036138771 @default.
- W4366991083 cites W2038730132 @default.
- W4366991083 cites W2039737144 @default.
- W4366991083 cites W2041922827 @default.
- W4366991083 cites W2044204440 @default.
- W4366991083 cites W2045391055 @default.
- W4366991083 cites W2049235730 @default.
- W4366991083 cites W2053432769 @default.
- W4366991083 cites W2060441889 @default.
- W4366991083 cites W2061135416 @default.
- W4366991083 cites W2062649036 @default.
- W4366991083 cites W2065919941 @default.
- W4366991083 cites W2069929255 @default.
- W4366991083 cites W2072522618 @default.
- W4366991083 cites W2072936983 @default.
- W4366991083 cites W2075556735 @default.
- W4366991083 cites W2076238138 @default.
- W4366991083 cites W2077958180 @default.
- W4366991083 cites W2082971123 @default.
- W4366991083 cites W2087036166 @default.
- W4366991083 cites W2088393247 @default.
- W4366991083 cites W2088909472 @default.
- W4366991083 cites W2089213864 @default.
- W4366991083 cites W2089656517 @default.
- W4366991083 cites W2093188448 @default.
- W4366991083 cites W2098659091 @default.
- W4366991083 cites W2102260493 @default.
- W4366991083 cites W2111332033 @default.
- W4366991083 cites W2120750395 @default.
- W4366991083 cites W2129264210 @default.
- W4366991083 cites W2129433521 @default.
- W4366991083 cites W2132741266 @default.
- W4366991083 cites W2158649798 @default.
- W4366991083 cites W2162691865 @default.
- W4366991083 cites W2163894214 @default.
- W4366991083 cites W2236388055 @default.
- W4366991083 cites W2269903369 @default.
- W4366991083 cites W2321533756 @default.
- W4366991083 cites W2424763930 @default.
- W4366991083 cites W2581534651 @default.
- W4366991083 cites W2586308577 @default.
- W4366991083 cites W2607421060 @default.
- W4366991083 cites W2609994856 @default.
- W4366991083 cites W2613689471 @default.
- W4366991083 cites W2762266207 @default.
- W4366991083 cites W2765682425 @default.
- W4366991083 cites W2769396631 @default.
- W4366991083 cites W2781877576 @default.
- W4366991083 cites W2790661377 @default.
- W4366991083 cites W2979435077 @default.
- W4366991083 cites W3009759002 @default.
- W4366991083 cites W3124364691 @default.
- W4366991083 cites W3129466855 @default.
- W4366991083 cites W99708900 @default.
- W4366991083 doi "https://doi.org/10.1117/1.nph.10.2.025005" @default.