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- W4378675698 abstract "To detect cytochrome c (Cyt c) as an important biomarker of apoptosis inside the cells, a simple, label-free, fluorometric detection method has been presented. For this purpose, an aptamer/gold nanocluster probe ([email protected]) was produced which could specifically bind to Cyt c leading to fluorescence quenching of AuNCs. The developed aptasensor showed two linear ranges of 1-80 μM and 100-1000 μM and a detection limit of 0.77 μM and 297.5 μM, respectively. This platform was successfully used to assay Cyt c release inside the apoptotic cells and their cell lysate. [email protected] due to its enzyme-like properties could replace antibodies in Cyt c detection by conventional blotting techniques." @default.
- W4378675698 created "2023-05-30" @default.
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- W4378675698 date "2023-11-01" @default.
- W4378675698 modified "2023-10-16" @default.
- W4378675698 title "A turn-off fluorimetric -aptasensor for early detection of apoptosis inside the cells" @default.
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- W4378675698 doi "https://doi.org/10.1016/j.saa.2023.122933" @default.
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