Matches in Ubergraph for { <http://purl.obolibrary.org/obo/GO_0097192> ?p ?o ?g. }
- GO_0097192 RO_0002320 NCBITaxon_1 @default.
- GO_0097192 RO_0002320 NCBITaxon_131567 @default.
- GO_0097192 RO_0002320 NCBITaxon_2759 @default.
- GO_0097192 RO_0002320 NCBITaxon_33154 @default.
- GO_0097192 RO_0002320 OBI_0100026 @default.
- GO_0097192 RO_0002320 PCO_0000031 @default.
- GO_0097192 RO_0002323 BFO_0000001 @default.
- GO_0097192 RO_0002323 BFO_0000003 @default.
- GO_0097192 RO_0002323 BFO_0000015 @default.
- GO_0097192 RO_0002323 COB_0000034 @default.
- GO_0097192 RO_0002323 COB_0000037 @default.
- GO_0097192 RO_0002323 GO_0006915 @default.
- GO_0097192 RO_0002323 GO_0007154 @default.
- GO_0097192 RO_0002323 GO_0008150 @default.
- GO_0097192 RO_0002323 GO_0008219 @default.
- GO_0097192 RO_0002323 GO_0009987 @default.
- GO_0097192 RO_0002323 GO_0012501 @default.
- GO_0097192 RO_0002323 GO_0023052 @default.
- GO_0097192 RO_0002323 GO_0050789 @default.
- GO_0097192 RO_0002323 GO_0050896 @default.
- GO_0097192 RO_0002323 GO_0051716 @default.
- GO_0097192 RO_0002323 GO_0065007 @default.
- GO_0097192 RO_0002410 BFO_0000001 @default.
- GO_0097192 RO_0002410 BFO_0000003 @default.
- GO_0097192 RO_0002410 BFO_0000015 @default.
- GO_0097192 RO_0002410 COB_0000034 @default.
- GO_0097192 RO_0002410 COB_0000037 @default.
- GO_0097192 RO_0002410 GO_0008150 @default.
- GO_0097192 RO_0002410 GO_0009987 @default.
- GO_0097192 RO_0002411 BFO_0000001 @default.
- GO_0097192 RO_0002411 BFO_0000003 @default.
- GO_0097192 RO_0002411 BFO_0000015 @default.
- GO_0097192 RO_0002411 COB_0000034 @default.
- GO_0097192 RO_0002411 COB_0000037 @default.
- GO_0097192 RO_0002411 GO_0008150 @default.
- GO_0097192 RO_0002411 GO_0009987 @default.
- GO_0097192 RO_0002418 BFO_0000001 @default.
- GO_0097192 RO_0002418 BFO_0000003 @default.
- GO_0097192 RO_0002418 BFO_0000015 @default.
- GO_0097192 RO_0002418 COB_0000034 @default.
- GO_0097192 RO_0002418 COB_0000037 @default.
- GO_0097192 RO_0002418 GO_0008150 @default.
- GO_0097192 RO_0002418 GO_0009987 @default.
- GO_0097192 RO_0002501 BFO_0000001 @default.
- GO_0097192 RO_0002501 BFO_0000003 @default.
- GO_0097192 RO_0002501 BFO_0000015 @default.
- GO_0097192 RO_0002501 COB_0000034 @default.
- GO_0097192 RO_0002501 COB_0000037 @default.
- GO_0097192 RO_0002501 GO_0008150 @default.
- GO_0097192 RO_0002501 GO_0009987 @default.
- GO_0097192 normalizedInformationContent "90.826665450122817" @default.
- GO_0097192 referenceCount "4" @default.
- GO_0097192 created_by "pr" @default.
- GO_0097192 creation_date "2011-11-23T09:37:09Z" @default.
- GO_0097192 hasExactSynonym "extrinsic apoptotic signalling pathway in absence of ligand" @default.
- GO_0097192 hasNarrowSynonym "extrinsic apoptosis in absence of ligand" @default.
- GO_0097192 hasOBONamespace "biological_process" @default.
- GO_0097192 hasRelatedSynonym "dependence receptor signaling pathway" @default.
- GO_0097192 id "GO:0097192" @default.
- GO_0097192 type Class @default.
- GO_0097192 comment "For dependence receptors, absence of a ligand or withdrawal of a ligand from a receptor acts as a signal. An example of 'extrinsic apoptotic signaling pathway in absence of ligand' is withdrawal of a growth factor such as NGF, even if traditionally apoptosis induced via growth factor withdrawal has been classified as an instance of intrinsic apoptosis. See an example in PMID:19767770. Ligands whose withdrawal or absence induce apoptosis should be annotated to GO:2001239 'regulation of extrinsic apoptotic signaling pathway in absence of ligand', rather than to the pathway term itself. Examples of gene products that may be annotated to GO:0097192 'extrinsic apoptotic signaling pathway in absence of ligand' include dependence receptors such as DCC or UNC5B, which relay lethal signals in the absence of their ligand (netrin-1). In the case of DCC and UNC5B, the signaling proceeds through the assembly of a DRAL- and TUCAN- (or NLRP1-) containing caspase-9-activating complex or by the dephosphorylation-mediated activation of death-associated protein kinase 1 (DAPK1) by UNC5B-bound protein phosphatase 2A (PP2A), respectively. DAPK1 can mediate the direct activation of executioner caspases or favor MOMP (reviewed in PMID:21760595). Also see PMID:21172653 (annotations to UNC5B and PR65beta, UniProt symbols O08722, PPP2R1B and P30154)." @default.
- GO_0097192 isDefinedBy go.owl @default.
- GO_0097192 label "extrinsic apoptotic signaling pathway in absence of ligand" @default.
- GO_0097192 subClassOf BFO_0000001 @default.
- GO_0097192 subClassOf BFO_0000003 @default.
- GO_0097192 subClassOf BFO_0000015 @default.
- GO_0097192 subClassOf COB_0000034 @default.
- GO_0097192 subClassOf COB_0000037 @default.
- GO_0097192 subClassOf GO_0007165 @default.
- GO_0097192 subClassOf GO_0007166 @default.
- GO_0097192 subClassOf GO_0008150 @default.
- GO_0097192 subClassOf GO_0009987 @default.
- GO_0097192 subClassOf GO_0038034 @default.
- GO_0097192 subClassOf GO_0050789 @default.
- GO_0097192 subClassOf GO_0050794 @default.
- GO_0097192 subClassOf GO_0065007 @default.
- GO_0097192 subClassOf GO_0097190 @default.
- GO_0097192 subClassOf GO_0097191 @default.
- GO_0097192 subClassOf GO_0097192 @default.
- GO_0097192 category BiologicalEntity @default.
- GO_0097192 category BiologicalProcess @default.
- GO_0097192 category BiologicalProcessOrActivity @default.
- GO_0097192 category Entity @default.
- GO_0097192 category NamedThing @default.
- GO_0097192 category Occurrent @default.
- GO_0097192 category OntologyClass @default.
- GO_0097192 category Pathway @default.
- GO_0097192 category PhysicalEssenceOrOccurrent @default.
- GO_0097192 category ThingWithTaxon @default.