Matches in Ubergraph for { ?s <http://www.w3.org/2000/01/rdf-schema#comment> ?o ?g. }
- CL_0000553 comment "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative." @default.
- CL_0000556 comment "Megakaryocytes are reportedly CD181-positive and CD182-positive." @default.
- CL_0000557 comment "Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative." @default.
- CL_0000559 comment "Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid." @default.
- CL_0000560 comment "Found in the Band 1 fraction." @default.
- CL_0000564 comment "These cells are CD11b-negative, CD15-positive, CD16-negative, CD49d-positive, CD68-positive, CD35-negative, and fMLP receptor-negative. They are found in the Band 3 fraction." @default.
- CL_0000566 comment "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive." @default.
- CL_0000576 comment "Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid." @default.
- CL_0000578 comment "This class has been re-labeled to imply reference only to in vitro experimentally modified cells, similarly, the definition has been slightly updated to reflect this. 'experimentally modified cell' refers only to cells in vitro, and not modified in vivo/in environment cells. There is currently no class representing unmodified in vitro cells (other than the parent 'cell in vitro'), or a class representing modified native cells. More granular subclassing of experimentally modified cell can be found in ReO. MHB 1.12.12" @default.
- CL_0000580 comment "These cells are also CD15-positive, CD35-negative, CD49d-positive, and fMLP receptor-negative. They are found in the Band 2 fraction." @default.
- CL_0000581 comment "Markers: Mouse: F4/80-high, CD11b-high, CD68+, SIGNR1+, Dectin-1+." @default.
- CL_0000582 comment "These cells are also CD35-negative, CD49d-positive, and fMLP receptor-negative. They are found in the Band 2 fraction." @default.
- CL_0000583 comment "Markers: Mouse: F4/80mid, CD11b-/low, CD11c+, CD68+, sialoadhesin+, dectin-1+, MR+, CX3CR1-." @default.
- CL_0000585 comment "This term is rather archaic; consider using 'natural killer cell ; CL:0000623', 'pro-B cell ; CL:0000826', 'pro-T cell ; CL:0000827', or other appropriate lymphocyte-related term depending on the context." @default.
- CL_0000594 comment "Skeletal muscle satellite cells are not traditionally referred to as myoblasts. They are a heterogeneous population whose division, following activiation, contributes to the formation of skeletal muscle fibers and to maintenance of the skeletal muscle statelite cell population." @default.
- CL_0000610 comment "This term was obsoleted as it is redundant with PO:0009002 in the cell ontology (PO)" @default.
- CL_0000611 comment "These cells are CD34-positive, CD45RA-negative, CD71-negative, and lineage-negative (CD2, CD3 epsilon, CD4, CD5, CD8a, CD14, CD19, CD20, integrin alpha-M, NCAM-1, SCA-1, Ly6G, Ly76)." @default.
- CL_0000613 comment "BaP are also CD13-low and integrin beta-7-low. They are lin-negative (CD2, CD3e, CD4, CD5, CD8, CD11b, CD14, CD19, CD20, ly6g, ly76, and NCAM-1). They also lack expression of mast cell protease 1 (MCP-1) and microphthalmia-associated transcription factor (mitf)." @default.
- CL_0000626 comment "Granule cells are the most abundant neuronal population in the olfactory bulb and are continuously renewed throughout life." @default.
- CL_0000628 comment "see PMID:21177950, The making of a photosynthetic animal." @default.
- CL_0000632 comment "Hepatic stellate cells are CD271-positive, desmin-positive, DDR-2-positive, GFAP-positive, synamin-positive, synaptophysin-positive, vimentin-positive, They are capable of producing angiotensin II, fibronectin, laminin, MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TGF-beta1, TIMP-1, TIMP-2, type I collagen, type III collagen, type IV collagen, and type VI collagen." @default.
- CL_0000642 comment "Folliculostellate cells are a heterogeneous group of cells rather than a single cell type, with different morphology and gene expression profiles. Due to this heterogeneity, it is unclear if different properties that have been attributed to folliculostellate cells (pluripotent, proliferative, phagocytic) are common in all folliculostellate cells or limited to particular subsets." @default.
- CL_0000647 comment "Role or process: Chronic infection, granulomatous inflammation. Consider also megakaryocyte (CL:0000556) as sometimes multinucleated giant cell is used to refer to this." @default.
- CL_0000650 comment "Do all of these cells really develop from some mesenchymal stem cell?" @default.
- CL_0000663 comment "https://github.com/obophenotype/cell-ontology/issues/726" @default.
- CL_0000664 comment "https://github.com/obophenotype/cell-ontology/issues/726" @default.
- CL_0000665 comment "https://github.com/obophenotype/cell-ontology/issues/726" @default.
- CL_0000668 comment "OBSOLETE: Term was made obsolete to avoid confusion with plant parenchymal cell. Cell type has a similar but slightly different meaning in botany (plants): see PO:0000074." @default.
- CL_0000669 comment "Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A." @default.
- CL_0000681 comment "Unlike that of mammals, the brain of adult teleost fish exhibits an intense and widespread neurogenic activity as a result of the persistence of radial glial cells acting as neural progenitors throughout life." @default.
- CL_0000682 comment "Should double check and see if M cells are particular to a specific region." @default.
- CL_0000695 comment "While previously called 'pioneer neurons' of the marginal zone, Cajal-Retzius cells are differentiated from pioneer neurons (which are Reln-negative) by their Reln-immunoreactivity." @default.
- CL_0000710 comment "The term "neuroepithelial cell" is used to describe both this cell type and sensory epithelial cell (CL:0000098)." @default.
- CL_0000717 comment "Term merged into CL:0008037. Refer to https://github.com/obophenotype/cell-ontology/issues/1364" @default.
- CL_0000718 comment "Not to be confused with the Semper cells of the Semper organ found in gastropods." @default.
- CL_0000726 comment "Considering obsoleting as sometimes used to refer to protozoans too. But reference indicates term was intended for fungus." @default.
- CL_0000727 comment "Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to primary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004231." @default.
- CL_0000728 comment "Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to secondary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004232." @default.
- CL_0000729 comment "Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to tertiary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004233." @default.
- CL_0000734 comment "Obsoleted as this is the same thing as 'embryonic plasmatocyte'." @default.
- CL_0000736 comment "Obsoleted as this term probably resulted from a confusion. Hemocytes are either derived from the embryonic head mesoderm ("embryonic hemocytes") or from the larval lymph gland ("lymph gland hemocytes"), not from an "embryonic gland"." @default.
- CL_0000743 comment "is hypertrophic pathological or normal? and can it be described using a pato term?" @default.
- CL_0000746 comment "This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction." @default.
- CL_0000762 comment "Note that this is a non-mammalian cell type. Use platelet ; CL:0000233 for thrombocytes (platelets) in mammals." @default.
- CL_0000764 comment "Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes." @default.
- CL_0000767 comment "Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive." @default.
- CL_0000771 comment "Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte." @default.
- CL_0000778 comment "Morphology: mononuclear, highly vesicular." @default.
- CL_0000779 comment "Morphology: multinucleated, highly vesicular." @default.
- CL_0000780 comment "Morphology: multinucleated, highly vesicular; location: roots of deciduous (milk) teeth." @default.
- CL_0000781 comment "Morphology: Mononuclear, highly vesicular; location: roots of deciduous (milk) teeth." @default.
- CL_0000782 comment "These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8)." @default.
- CL_0000785 comment "Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive." @default.
- CL_0000786 comment "Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive." @default.
- CL_0000787 comment "Memory B-cells are also reportedly CD5-negative, CD10-negative, CD21-positive, CD22-positive, CD23-negative, CD24-positive, CD25-positive, CD27-positive, CD34-negative, CD38-negative, CD40-positive, CD43-negative, CD44-positive, CD45-positive, CD53-positive, CD80-negative, CD81-negative, CD86-positive, and CD196/CCR6-positive." @default.
- CL_0000788 comment "This cell type is compatible with the HIPC Lyoplate markers for 'naive B cell'. Per DSD: Naive B cells are also reportedly CD10-negative, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD25-negative, CD27-negative, CD34-negative, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD80-negative, CD81-positive, CD84-positive, CD86-negative, CD95-negative, CD138-negative, CD150-positive, CD184/CXCR4-positive, CD185/CXCR5-positive, CD196/CCR6-positive, CD200-positive, CD229-positive, CD243-positive, CD289-positive, CD290-positive, CD352-positive, MHCII/HLA-DR-positive, cadherin 9-positive, and sIgH-positive, Transcription factors: Pax5-positive, ETS1-positive, FOXO1A-positive, KLF4-positive, KLF9-positive, MiTF-positive, OBF1-positive, PLZF-positive, and SpiB-positive." @default.
- CL_0000792 comment "This cell type is compatible with the HIPC Lyoplate markers for 'Treg'. The inclusion of CD127lo in the logical definition is compatible with both human and mouse T cells of this subtype." @default.
- CL_0000794 comment "Note that while T cells of this subset are loosely referred to 'cytotoxic T cells,' as many other T cell types, including CD4-positive, alpha-beta T cells and gamma-delta T cells exhibit cytotoxicity in vitro and in vivo." @default.
- CL_0000798 comment "Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways." @default.
- CL_0000799 comment "Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways." @default.
- CL_0000805 comment "Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and rearranging the T cell receptor alpha chain and expressing the CD8 coreceptor. This stage comes between the DN4 and DP stages." @default.
- CL_0000806 comment "Note that this type of thymocyte is at the earliest stage of T cell receptor rearrangement of the beta, gamma, and delta T cell receptor chains. Also, there is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'." @default.
- CL_0000807 comment "There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'." @default.
- CL_0000808 comment "Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and beginning to rearrange the T cell receptor alpha chain. There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'." @default.
- CL_0000809 comment "Thymocytes of this stage are undergoing positive and negative selection." @default.
- CL_0000815 comment "This cell type may express FoxP3 and CD25 and secretes IL-10 and TGF-beta." @default.
- CL_0000816 comment "Immature B cells are also reportedly CD5-positive, CD10-positive, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD24-positive, CD25-negative, CD27-negative, CD34-negative, CD38-positive, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD79a-positive, CD80-negative, CD81-positive, CD86-negative, CD95-negative, CD127-negative, CD138-negative, CD185-positive, CD196-positive, MHCII/HLA-DR-positive, RAG-positive, TdT-negative, Vpre-B-negative, and preBCR-negative. Transcription factors expressed: Pax5-positive." @default.
- CL_0000818 comment "This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'." @default.
- CL_0000819 comment "There are small numbers of B-1 cells found in the lymph nodes and spleen, while larger numbers can be found in the peritoneal and pleural cavities. B-1 B cells are reportedly CD11b-positive, CD20-positive, CD21-positive, CD27-positive, CD44-positive, CD45RB-positive, CD48-positive, CD70-negative, CD150-positive, CD244-negative, CD352-positive, sIgM-positive, and sIgD-low." @default.
- CL_0000822 comment "B-2 B cells are reportedly CD48-positive, CD244-negative, and CD352-positive." @default.
- CL_0000823 comment "In mouse the NKR are Ly49 molecules and in human these cells express KIR molecules." @default.
- CL_0000825 comment "Most markers only described for human pro NK cells." @default.
- CL_0000826 comment "Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative." @default.
- CL_0000828 comment "Note that this is a non-mammalian cell type." @default.
- CL_0000831 comment "MCP are CD16-positive, CD32-positive, CD34-positive, CD45-positive, integrin beta-7-positive, and lin-negative (CD2, CD3e, CD4, CD5, CD8a, CD14, CD19, CD20, CD27, integrin alpha-M, ly6c, ly6g, NCAM-1, and ter119). These cells also express the transcription factors GATA-1, GATA-2, and MITF, but not C/EBPa." @default.
- CL_0000837 comment "Markers differ between mouse and human." @default.
- CL_0000838 comment "Note that this is a class of cell types, not an identified single cell type." @default.
- CL_0000839 comment "Note that this is a class of cell types, not an identified single cell type." @default.
- CL_0000843 comment "Follicular B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive." @default.
- CL_0000844 comment "Germinal center B cells are also reportedly CD10-positive, CD19-positive, CD20-positive, CD38-positive, CD44-low, CD45-positive, CD48-positive, CD95-positive, CD352-positive, and HLA-DR-positive. Transcription factors: BCL6-positive, Ets1-positive, IRF8-positive, MTA3-positive, OBF1-positive, PAX5-positive, SpiB-positive, and STAT3-positive." @default.
- CL_0000845 comment "MZ B cells are reportedly CD1-positive (mice), CD20-positive, CD48-positive, CD84-positive, CD150-positive, CD229-positive, and CD352-positive." @default.
- CL_0000860 comment "Markers: CCR2+CXCCR1<low> (human, mouse, rat)." @default.
- CL_0000861 comment "Markers: CD11b+, CD68+; Mouse: F4/80+; role or process: immune, inflammation (inflammatory response)." @default.
- CL_0000862 comment "Markers: May express: IL10, TGFbeta." @default.
- CL_0000863 comment "Markers: Express: TNFa, IL1b, IL6, iNOS, NADPH-oxidase; produce: reactive oxygen species, nitric oxide; role or process: immune, inflammation (inflammatory response)." @default.
- CL_0000866 comment "Role or process: immune, clearance of apoptotic thymocytes, antigen-presentation." @default.
- CL_0000868 comment "Marker was observed on rat cells." @default.
- CL_0000871 comment "Role or process: immune, clearance of apoptotic and senescent cells." @default.
- CL_0000872 comment "Markers: Mouse: F4/80-, MARCO+, SR-A+, SIGN-R1+, Dectin2+." @default.
- CL_0000873 comment "Markers: Mouse: F4/80-, Dectin2-low, sialoadhesin+." @default.
- CL_0000874 comment "Markers: Mouse: F4/80+, CD68+, MR+, Dectin2+, macrosialin+, sialoadhesin-low; role or process: immune, clearance of senescent erythrocytes." @default.
- CL_0000875 comment "Markers: CCR2-CX3CCR1+ (human, mouse, rat); human: CD16+, CCR5+, CD32/FcgRII-high, MHCII+, CD86+; mouse: CD62L-Ly6C-." @default.
- CL_0000876 comment "Markers: Mouse: F4/80-, CD68+, macrosialin+." @default.
- CL_0000881 comment "Markers: Human/monkey, mice: CD163. Human: CD14+CD16+CD163+." @default.
- CL_0000889 comment "Markers: Mouse: CD11b+GR1+CD31+; Human: CD34+ CD33+CD15-CD13+. (According to some reports in humans these cells are iNOS+ARG1+IL13+IFNg+); location: In cancerous tissue; in the blood and lymphoid organs in sepsis." @default.
- CL_0000890 comment "Role or process: tissue remodeling." @default.
- CL_0000895 comment "These cells have not been exposed to antigen following thymic T-cell selection; found in blood and secondary lymphoid organs. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD4+ T cell', but includes additional markers known to be expressed on naive CD4+ T cells." @default.
- CL_0000899 comment "This cell type is compatible with the HIPC Lyoplate markers for 'Th17 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 17 T cells." @default.
- CL_0000900 comment "This cell traffics in secondary lymphoid organs and blood. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD8+ T cell', but includes additional markers known to be expressed on naive CD8+ T cells." @default.
- CL_0000901 comment "These cells are reportedly induced by IL-10 and are capable of producing IFN-gamma, IL-5, IL-10, and TGF-beta.)" @default.