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- FBcv_0005059 IAO_0000115 "Transactivator ('driver') that is encoded by a transgenic locus or modified endogenous locus and which forms part of a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder." @default.
- FBcv_0005059 contributor 0000-0002-0027-0858 @default.
- FBcv_0005059 date "2017-06-28T11:41:27.000Z" @default.
- FBcv_0005059 normalizedInformationContent "90.826665450122817" @default.
- FBcv_0005059 referenceCount "4" @default.
- FBcv_0005059 hasOBONamespace "experimental_tool_descriptor" @default.
- FBcv_0005059 id "FBcv:0005059" @default.
- FBcv_0005059 inSubset common_tool_use @default.
- FBcv_0005059 type Class @default.
- FBcv_0005059 isDefinedBy fbcv.owl @default.
- FBcv_0005059 label "binary expression system - driver" @default.
- FBcv_0005059 subClassOf FBcv_0000000 @default.
- FBcv_0005059 subClassOf FBcv_0000013 @default.
- FBcv_0005059 subClassOf FBcv_0005001 @default.
- FBcv_0005059 subClassOf FBcv_0005058 @default.
- FBcv_0005059 subClassOf FBcv_0005059 @default.