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- FBcv_0005067 IAO_0000115 "Repressor that can be used to regulate expression in a binary expression system and whose activity is regulated by temperature. A binary expression system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder. Use of a temperature conditional repressor permits further refinement of this expression pattern." @default.
- FBcv_0005067 contributor 0000-0002-0027-0858 @default.
- FBcv_0005067 date "2017-12-13T13:17:30.000Z" @default.
- FBcv_0005067 normalizedInformationContent "100" @default.
- FBcv_0005067 referenceCount "1" @default.
- FBcv_0005067 hasOBONamespace "experimental_tool_descriptor" @default.
- FBcv_0005067 id "FBcv:0005067" @default.
- FBcv_0005067 type Class @default.
- FBcv_0005067 isDefinedBy fbcv.owl @default.
- FBcv_0005067 label "binary expression system - temperature conditional repressor" @default.
- FBcv_0005067 subClassOf FBcv_0000000 @default.
- FBcv_0005067 subClassOf FBcv_0000013 @default.
- FBcv_0005067 subClassOf FBcv_0005001 @default.
- FBcv_0005067 subClassOf FBcv_0005058 @default.
- FBcv_0005067 subClassOf FBcv_0005061 @default.
- FBcv_0005067 subClassOf FBcv_0005066 @default.
- FBcv_0005067 subClassOf FBcv_0005067 @default.