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- MI_0657 IAO_0000115 "RNA and cDNA constructs with variable central sequences and a constant flanking region are collected in a complex library. The library is then screened to select either specific binding partners of a bait molecule (generally a protein) or particular enzymatic activities of the nucleic acid molecules themselves. The selected nucleic acids are amplified using the constant flanking regions to increase their abundance. Cycles of selection-amplification can be repeated to increase the specificity of the targets that, at the end, are individually identified by sequencing." @default.
- MI_0657 normalizedInformationContent "100" @default.
- MI_0657 referenceCount "1" @default.
- MI_0657 hasExactSynonym "in vitro evolution of nucleic acids" @default.
- MI_0657 hasExactSynonym "selex" @default.
- MI_0657 hasOBONamespace "PSI-MI" @default.
- MI_0657 id "MI:0657" @default.
- MI_0657 inSubset PSI-MI_slim @default.
- MI_0657 type Class @default.
- MI_0657 isDefinedBy mi.owl @default.
- MI_0657 label "systematic evolution of ligands by exponential enrichment" @default.
- MI_0657 subClassOf MI_0000 @default.
- MI_0657 subClassOf MI_0001 @default.
- MI_0657 subClassOf MI_0045 @default.
- MI_0657 subClassOf MI_0400 @default.
- MI_0657 subClassOf MI_0401 @default.
- MI_0657 subClassOf MI_0657 @default.