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- MI_0900 IAO_0000115 "pVIII is the major coat protein of filamentous phage. Its amino-terminus is exposed to solvent and tolerates the insertion of relatively large peptide fragments. By inserting the peptide coding sequence into the phage copy of the pVIII gene up to 3000 copies of the hybrid proteins can be displayed along the phage capsid. Alternatively the hybrid protein can be encoded on a phagemid that is incorporated in a virus like particle by infection with a helper phage. In this latter case one obtains a chimeric capsid where hybrid proteins are interspersed at different density in an otherwise wild type coat. Because of the high copy number pVIII display is also referred to as high valency display." @default.
- MI_0900 normalizedInformationContent "100" @default.
- MI_0900 referenceCount "1" @default.
- MI_0900 hasExactSynonym "high valency display" @default.
- MI_0900 hasExactSynonym "p8 filamentous phage" @default.
- MI_0900 hasOBONamespace "PSI-MI" @default.
- MI_0900 id "MI:0900" @default.
- MI_0900 inSubset PSI-MI_slim @default.
- MI_0900 type Class @default.
- MI_0900 isDefinedBy mi.owl @default.
- MI_0900 label "p8 filamentous phage display" @default.
- MI_0900 subClassOf MI_0000 @default.
- MI_0900 subClassOf MI_0001 @default.
- MI_0900 subClassOf MI_0034 @default.
- MI_0900 subClassOf MI_0045 @default.
- MI_0900 subClassOf MI_0048 @default.
- MI_0900 subClassOf MI_0084 @default.
- MI_0900 subClassOf MI_0400 @default.
- MI_0900 subClassOf MI_0401 @default.
- MI_0900 subClassOf MI_0900 @default.