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- MI_1086 IAO_0000115 "Two chambers are separated by a dialysis membrane. The molecular weight cut off (MWCO) of this membrane is chosen such that it will retain the receptor component of the sample (the element which will bind the ligand). A known concentration and volume of ligand is placed into one of the chambers. The ligand is small enough to pass freely through the membrane. A known concentration of receptor is then placed in the remaining chamber in an equivalent volume to that placed in the first chamber. As the ligand diffuses across the membrane some of it will bind to the receptor and some will remain free in solution. The higher the affinity of the interaction, the higher the concentration of ligand that will be bound at any time." @default.
- MI_1086 normalizedInformationContent "100" @default.
- MI_1086 referenceCount "1" @default.
- MI_1086 created_by "orchard" @default.
- MI_1086 creation_date "2011-07-05T11:12:25Z" @default.
- MI_1086 hasExactSynonym "equilib. dialysis" @default.
- MI_1086 hasOBONamespace "PSI-MI" @default.
- MI_1086 id "MI:1086" @default.
- MI_1086 type Class @default.
- MI_1086 isDefinedBy mi.owl @default.
- MI_1086 label "equilibrium dialysis" @default.
- MI_1086 subClassOf MI_0000 @default.
- MI_1086 subClassOf MI_0001 @default.
- MI_1086 subClassOf MI_0013 @default.
- MI_1086 subClassOf MI_0045 @default.
- MI_1086 subClassOf MI_1086 @default.