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- MI_1174 IAO_0000115 "Multivalent ligands form multiple discrete interactions with one or more binding partners. In some cases, An initial binding event can pre-organize other sites for binding. This reduces the degrees of freedom of these sites, thus reducing the entropic costs of their interactions. In addition, the combined strength of multiple interactions increases the enthalpic stability of each interaction (avidity effect). As a result of such effects, interactions of this kind can have a cooperative effect on subsequent interactions." @default.
- MI_1174 normalizedInformationContent "100" @default.
- MI_1174 referenceCount "1" @default.
- MI_1174 created_by "orchard" @default.
- MI_1174 creation_date "2012-06-07T01:29:13Z" @default.
- MI_1174 hasOBONamespace "PSI-MI" @default.
- MI_1174 id "MI:1174" @default.
- MI_1174 inSubset PSI-MI_slim @default.
- MI_1174 type Class @default.
- MI_1174 isDefinedBy mi.owl @default.
- MI_1174 label "configurational pre-organization" @default.
- MI_1174 subClassOf MI_0000 @default.
- MI_1174 subClassOf MI_0590 @default.
- MI_1174 subClassOf MI_0664 @default.
- MI_1174 subClassOf MI_1149 @default.
- MI_1174 subClassOf MI_1170 @default.
- MI_1174 subClassOf MI_1174 @default.