Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C101255> ?p ?o ?g. }
Showing items 1 to 28 of
28
with 100 items per page.
- NCIT_C101255 IAO_0000115 "A class of agents that act by selectively inhibiting aldosterone receptor activation with diuretic activity. Aldosterone receptor antagonists bind to and block the activation of aldosterone (mineralocorticoid) receptors on the epithelial cells in the late distal tubule and collecting duct of the kidney, thus preventing the synthesis of aldosterone-induced proteins which enhance Na+ retention and K+ and H+ secretion. The enhanced excretion of Na+ produces diuresis ultimately resulting in a reduction in blood pressure without the loss of K+." @default.
- NCIT_C101255 NCIT_A48 NCIT_C17998 @default.
- NCIT_C101255 NCIT_A48 NCIT_C49487 @default.
- NCIT_C101255 NCIT_A48 NCIT_C49488 @default.
- NCIT_C101255 NCIT_NHC0 "C101255" @default.
- NCIT_C101255 NCIT_P106 "Chemical Viewed Functionally" @default.
- NCIT_C101255 NCIT_P108 "Aldosterone Receptor Antagonist" @default.
- NCIT_C101255 NCIT_P207 "C3536833" @default.
- NCIT_C101255 NCIT_P322 "ACC/AHA" @default.
- NCIT_C101255 NCIT_P325 "Spironolactone or eplerenone, which antagonize the action of aldosterone at mineralocorticoid receptors" @default.
- NCIT_C101255 normalizedInformationContent "89.350088392419622" @default.
- NCIT_C101255 referenceCount "5" @default.
- NCIT_C101255 hasExactSynonym "Aldosterone Receptor Antagonist" @default.
- NCIT_C101255 hasExactSynonym "Aldosterone inhibitor (mineralocorticoid receptor antagonist)" @default.
- NCIT_C101255 hasExactSynonym "Antimineralocorticoid" @default.
- NCIT_C101255 inSubset NCIT_C191200 @default.
- NCIT_C101255 inSubset NCIT_C191387 @default.
- NCIT_C101255 inSubset NCIT_C191405 @default.
- NCIT_C101255 inSubset NCIT_C191670 @default.
- NCIT_C101255 type Class @default.
- NCIT_C101255 isDefinedBy ncit.owl @default.
- NCIT_C101255 label "Aldosterone Receptor Antagonist" @default.
- NCIT_C101255 subClassOf NCIT_C101255 @default.
- NCIT_C101255 subClassOf NCIT_C147908 @default.
- NCIT_C101255 subClassOf NCIT_C1908 @default.
- NCIT_C101255 subClassOf NCIT_C1909 @default.
- NCIT_C101255 subClassOf NCIT_C2355 @default.
- NCIT_C101255 subClassOf NCIT_C547 @default.