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- NCIT_C101788 IAO_0000115 "An endotoxin and biologically active component of the Gram-negative bacterial cell wall that is a Toll-like receptor 4 (TLR4) agonist with potential immunostimulatory activity. Upon internalization, lipopolysaccharide (LPS) activates TLR4 which in turn activates the NFkappaB pathway, in addition to mitogen-activated protein kinases signaling pathways. This leads to the release of proinflammatory cytokines and stimulates an innate immune response against vaccine antigens." @default.
- NCIT_C101788 NCIT_NHC0 "C101788" @default.
- NCIT_C101788 NCIT_P106 "Organic Chemical" @default.
- NCIT_C101788 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C101788 NCIT_P107 "Lipopolysaccharide" @default.
- NCIT_C101788 NCIT_P108 "Lipopolysaccharide" @default.
- NCIT_C101788 NCIT_P207 "C0023810" @default.
- NCIT_C101788 NCIT_P322 "CTRP" @default.
- NCIT_C101788 NCIT_P329 "732862" @default.
- NCIT_C101788 NCIT_P330 "732862" @default.
- NCIT_C101788 NCIT_P368 "CHEBI:16412" @default.
- NCIT_C101788 NCIT_P399 "732862" @default.
- NCIT_C101788 normalizedInformationContent "100" @default.
- NCIT_C101788 referenceCount "1" @default.
- NCIT_C101788 hasExactSynonym "LPS" @default.
- NCIT_C101788 hasExactSynonym "Lipopolysaccharide" @default.
- NCIT_C101788 inSubset NCIT_C116977 @default.
- NCIT_C101788 inSubset NCIT_C142799 @default.
- NCIT_C101788 inSubset NCIT_C176424 @default.
- NCIT_C101788 type Class @default.
- NCIT_C101788 isDefinedBy ncit.owl @default.
- NCIT_C101788 label "Lipopolysaccharide" @default.
- NCIT_C101788 subClassOf NCIT_C101788 @default.
- NCIT_C101788 subClassOf NCIT_C1908 @default.
- NCIT_C101788 subClassOf NCIT_C1909 @default.
- NCIT_C101788 subClassOf NCIT_C2139 @default.
- NCIT_C101788 subClassOf NCIT_C308 @default.