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- NCIT_C102747 IAO_0000115 "A derivative of pyridoxyl ethyldiamine (PLED) and mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with antioxidant, metal chelating and potential chemoprotective activities. Upon administration, PLED-based MnSOD mimetic mimics MnSOD and scavenges oxygen free radicals such as superoxide anion, hydrogen peroxide, and hydroxyl radical, thereby preventing oxygen free radical damage to macromolecules such as DNA and minimizing oxygen free radical-related chemotoxicity in normal tissues. In addition, this agent is able to strongly bind to iron." @default.
- NCIT_C102747 NCIT_NHC0 "C102747" @default.
- NCIT_C102747 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C102747 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C102747 NCIT_P107 "PLED-based MnSOD Mimetic" @default.
- NCIT_C102747 NCIT_P108 "PLED-based MnSOD Mimetic" @default.
- NCIT_C102747 NCIT_P208 "CL437004" @default.
- NCIT_C102747 NCIT_P210 "1401243-67-1" @default.
- NCIT_C102747 NCIT_P319 "N0JZU0WGU5" @default.
- NCIT_C102747 NCIT_P322 "CTRP" @default.
- NCIT_C102747 NCIT_P322 "FDA" @default.
- NCIT_C102747 NCIT_P329 "735792" @default.
- NCIT_C102747 NCIT_P330 "735792" @default.
- NCIT_C102747 NCIT_P399 "735792" @default.
- NCIT_C102747 normalizedInformationContent "100" @default.
- NCIT_C102747 referenceCount "1" @default.
- NCIT_C102747 hasExactSynonym "CALMANGAFODIPIR" @default.
- NCIT_C102747 hasExactSynonym "PLED-based MnSOD Mimetic" @default.
- NCIT_C102747 hasExactSynonym "PLEDOx" @default.
- NCIT_C102747 hasExactSynonym "PP-095" @default.
- NCIT_C102747 inSubset NCIT_C116977 @default.
- NCIT_C102747 inSubset NCIT_C116978 @default.
- NCIT_C102747 inSubset NCIT_C176424 @default.
- NCIT_C102747 inSubset NCIT_C63923 @default.
- NCIT_C102747 type Class @default.
- NCIT_C102747 isDefinedBy ncit.owl @default.
- NCIT_C102747 label "PLED-based MnSOD Mimetic" @default.
- NCIT_C102747 subClassOf NCIT_C102747 @default.
- NCIT_C102747 subClassOf NCIT_C1908 @default.
- NCIT_C102747 subClassOf NCIT_C1909 @default.
- NCIT_C102747 subClassOf NCIT_C26170 @default.
- NCIT_C102747 subClassOf NCIT_C275 @default.