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- NCIT_C102789 IAO_0000115 "Inducible regulatory T-lymphocytes that express CD4, CD25 (the alpha chain of the interleukin 2 receptor) and forkhead box P3 (FOXP3), with potential immunomodulating activity. Inducible CD4+CD25+ T regulatory cells (iTregs) are a subset of CD4+ T lymphocytes that are induced from CD25- precursors in peripheral lymphoid organs with interleukin-2 and transforming growth factor-beta. These regulatory T cells are essential in maintaining immunologic homeostasis. They may also prevent autoimmunity by suppressing self-reactive T cells, and may induce tolerance to allogeneic organ transplants such as in hematopoietic stem cell transplants." @default.
- NCIT_C102789 NCIT_NHC0 "C102789" @default.
- NCIT_C102789 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C102789 NCIT_P107 "Inducible CD4+CD25+ Regulatory T Cells" @default.
- NCIT_C102789 NCIT_P108 "Inducible CD4+CD25+ Regulatory T Cells" @default.
- NCIT_C102789 NCIT_P208 "CL437026" @default.
- NCIT_C102789 NCIT_P322 "CTRP" @default.
- NCIT_C102789 NCIT_P329 "737145" @default.
- NCIT_C102789 NCIT_P330 "737145" @default.
- NCIT_C102789 NCIT_P399 "737145" @default.
- NCIT_C102789 normalizedInformationContent "100" @default.
- NCIT_C102789 referenceCount "1" @default.
- NCIT_C102789 hasExactSynonym "Inducible CD4+CD25+ Regulatory T Cells" @default.
- NCIT_C102789 hasExactSynonym "iTregs" @default.
- NCIT_C102789 inSubset NCIT_C116977 @default.
- NCIT_C102789 inSubset NCIT_C116978 @default.
- NCIT_C102789 inSubset NCIT_C176424 @default.
- NCIT_C102789 type Class @default.
- NCIT_C102789 isDefinedBy ncit.owl @default.
- NCIT_C102789 label "Inducible CD4+CD25+ Regulatory T Cells" @default.
- NCIT_C102789 subClassOf NCIT_C102789 @default.
- NCIT_C102789 subClassOf NCIT_C142078 @default.
- NCIT_C102789 subClassOf NCIT_C1908 @default.
- NCIT_C102789 subClassOf NCIT_C1909 @default.
- NCIT_C102789 subClassOf NCIT_C307 @default.
- NCIT_C102789 subClassOf NCIT_C308 @default.