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- NCIT_C103150 IAO_0000115 "A specific biomarker of hypochlorous acid (HClO), the oxidation product of myeloperoxidase (MPO). Under oxidative stress, 3-chlorotyrosine is produced in proteins with tyrosine residues by the strong oxidant HClO. HClO which is formed at sites of inflammation is also the anti-bacterial molecule produced by neutrophils through MPO-catalyzed oxidation. MPO is a heme-containing enzyme secreted by activated neutrophils and monocytes; it is the only enzyme that produces HClO. Therefore, 3-chlorotyrosine can potentially be used to help determine the extent of neutrophilic inflammation." @default.
- NCIT_C103150 NCIT_NHC0 "C103150" @default.
- NCIT_C103150 NCIT_P106 "Organic Chemical" @default.
- NCIT_C103150 NCIT_P108 "3-Chlorotyrosine" @default.
- NCIT_C103150 NCIT_P207 "C0254781" @default.
- NCIT_C103150 NCIT_P210 "7423-93-0" @default.
- NCIT_C103150 NCIT_P319 "SY44C9MINA" @default.
- NCIT_C103150 NCIT_P322 "FDA" @default.
- NCIT_C103150 normalizedInformationContent "100" @default.
- NCIT_C103150 referenceCount "1" @default.
- NCIT_C103150 hasExactSynonym "3-CHLOROTYROSINE" @default.
- NCIT_C103150 hasExactSynonym "3-Chloro-L-Tyrosine" @default.
- NCIT_C103150 hasExactSynonym "3-Chlorotyrosine" @default.
- NCIT_C103150 hasExactSynonym "Chlorotyrosine" @default.
- NCIT_C103150 hasExactSynonym "Cl-Tyr" @default.
- NCIT_C103150 hasExactSynonym "L-(8CI)-3-Chloro-Tyrosine" @default.
- NCIT_C103150 hasExactSynonym "Monochlorotyrosine" @default.
- NCIT_C103150 inSubset NCIT_C63923 @default.
- NCIT_C103150 type Class @default.
- NCIT_C103150 isDefinedBy ncit.owl @default.
- NCIT_C103150 label "3-Chlorotyrosine" @default.
- NCIT_C103150 subClassOf NCIT_C103150 @default.
- NCIT_C103150 subClassOf NCIT_C1908 @default.
- NCIT_C103150 subClassOf NCIT_C1913 @default.
- NCIT_C103150 subClassOf NCIT_C200714 @default.
- NCIT_C103150 subClassOf NCIT_C232 @default.
- NCIT_C103150 subClassOf NCIT_C718 @default.
- NCIT_C103150 subClassOf NCIT_C73539 @default.