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- NCIT_C103178 IAO_0000115 "A dietary supplement containing the modified citrus pectin (MCP) derived from the soluble fiber of citrus fruit peels and a galectin-3 inhibitor with potential antioxidant, hypocholesterolemic, immunostimulatory, metal chelating, and anti-metastatic activities. MCP is a low molecular weight version of pectin composed of short, slightly-branched carbohydrate chains and is modified for enhanced absorbability. The bioactive fragments, most likely the galactan-containing portion, of pectin binds to galectin-3, a carbohydrate-binding protein involved in imflammation, heart disease and is upregulated on the surface of certain types of tumor cells. Binding of MCP may result in the suppression of cancer cell aggregation, adhesion, proliferation and metastasis. In addition, MCP decreases prostate specific antigen (PSA) levels and may remove heavy metals. Also, unsaturated oligogalacturonic acids in MCP may stimulate the immune system through the activation of natural killer cells, cytotoxic T-cells, and B-cells." @default.
- NCIT_C103178 NCIT_NHC0 "C103178" @default.
- NCIT_C103178 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C103178 NCIT_P108 "Modified Citrus Pectin Supplement" @default.
- NCIT_C103178 NCIT_P208 "CL437425" @default.
- NCIT_C103178 NCIT_P329 "740207" @default.
- NCIT_C103178 NCIT_P330 "740207" @default.
- NCIT_C103178 NCIT_P399 "740207" @default.
- NCIT_C103178 normalizedInformationContent "100" @default.
- NCIT_C103178 referenceCount "1" @default.
- NCIT_C103178 hasExactSynonym "Modified Citrus Pectin Supplement" @default.
- NCIT_C103178 hasExactSynonym "PectaSol-C" @default.
- NCIT_C103178 inSubset NCIT_C128784 @default.
- NCIT_C103178 inSubset NCIT_C176424 @default.
- NCIT_C103178 type Class @default.
- NCIT_C103178 isDefinedBy ncit.owl @default.
- NCIT_C103178 label "Modified Citrus Pectin Supplement" @default.
- NCIT_C103178 subClassOf NCIT_C103178 @default.
- NCIT_C103178 subClassOf NCIT_C1505 @default.
- NCIT_C103178 subClassOf NCIT_C1908 @default.