Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C103192> ?p ?o ?g. }
Showing items 1 to 28 of
28
with 100 items per page.
- NCIT_C103192 IAO_0000115 "A whole cell vaccine derived from a distinct subset of dendritic cells (DCs) with a plasma cell-like morphology that exhibits immunomodulating activity. Plasmacytoid dendritic cells (pDCs) express a characteristic set of surface markers, such as CD123 (interleukin-3 receptor alpha chain), BDCA-2 (blood dendritic cell antigen 2; CD303) and BDCA-4 (CD304), as well as intracellular toll-like receptors 7 and 9. Upon stimulation, the activated pDCs produce substantial amounts of interferon (IFN) alpha, and to a lesser degree IFN-beta, as well as other cytokines and chemokines, such as tumor necrosis factor alpha and interleukins 1, 6 and 8. In addition, these pDCs, directly or indirectly stimulate T-cells, B-cells and natural killer cells. This may potentially lead to increased immunity against tumor cells." @default.
- NCIT_C103192 NCIT_NHC0 "C103192" @default.
- NCIT_C103192 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C103192 NCIT_P108 "Plasmacytoid Dendritic Cell Vaccine" @default.
- NCIT_C103192 NCIT_P208 "CL437432" @default.
- NCIT_C103192 NCIT_P329 "740763" @default.
- NCIT_C103192 NCIT_P330 "740763" @default.
- NCIT_C103192 NCIT_P399 "740763" @default.
- NCIT_C103192 normalizedInformationContent "100" @default.
- NCIT_C103192 referenceCount "1" @default.
- NCIT_C103192 hasExactSynonym "Plasmacytoid Dendritic Cell Vaccine" @default.
- NCIT_C103192 hasExactSynonym "pDC Vaccine" @default.
- NCIT_C103192 inSubset NCIT_C128784 @default.
- NCIT_C103192 inSubset NCIT_C176424 @default.
- NCIT_C103192 type Class @default.
- NCIT_C103192 isDefinedBy ncit.owl @default.
- NCIT_C103192 label "Plasmacytoid Dendritic Cell Vaccine" @default.
- NCIT_C103192 subClassOf NCIT_C103192 @default.
- NCIT_C103192 subClassOf NCIT_C129820 @default.
- NCIT_C103192 subClassOf NCIT_C1663 @default.
- NCIT_C103192 subClassOf NCIT_C1908 @default.
- NCIT_C103192 subClassOf NCIT_C1909 @default.
- NCIT_C103192 subClassOf NCIT_C274 @default.
- NCIT_C103192 subClassOf NCIT_C28308 @default.
- NCIT_C103192 subClassOf NCIT_C28310 @default.
- NCIT_C103192 subClassOf NCIT_C307 @default.
- NCIT_C103192 subClassOf NCIT_C308 @default.
- NCIT_C103192 subClassOf NCIT_C923 @default.