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- NCIT_C103196 IAO_0000115 "A radioconjugate and glutamine analog consisting of the fluorine F 18 labeled 2S, 4R stereoisomer of 4-fluoroglutamine with potential use as a metabolic tracer for tumor imaging. Upon intravenous administration, fluorine F 18 4-L-fluoroglutamine (2S,4R) is preferentially taken up by cancer cells, possibly driven by c-Myc upregulation. Upon positron emission tomography (PET), cancer cells can be imaged. Tumor cells use the amino acid glutamine for nutritional purposes necessary for energy production and growth; as tumor cells proliferate more rapidly than normal healthy cells, glutamine uptake is higher in certain cancer cells." @default.
- NCIT_C103196 NCIT_NHC0 "C103196" @default.
- NCIT_C103196 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C103196 NCIT_P107 "Fluorine F 18 4-L-fluoroglutamine (2S,4R)" @default.
- NCIT_C103196 NCIT_P108 "Fluorine F 18 4-L-fluoroglutamine (2S,4R)" @default.
- NCIT_C103196 NCIT_P208 "CL437435" @default.
- NCIT_C103196 NCIT_P322 "CTRP" @default.
- NCIT_C103196 NCIT_P329 "741122" @default.
- NCIT_C103196 NCIT_P330 "741122" @default.
- NCIT_C103196 NCIT_P399 "741122" @default.
- NCIT_C103196 normalizedInformationContent "100" @default.
- NCIT_C103196 referenceCount "1" @default.
- NCIT_C103196 hasExactSynonym "18F Fluoroglutamine" @default.
- NCIT_C103196 hasExactSynonym "Fluorine F 18 4-L-fluoroglutamine (2S,4R)" @default.
- NCIT_C103196 hasExactSynonym "[18F] 4-L-fluoroglutamine (2S,4R)" @default.
- NCIT_C103196 inSubset NCIT_C116977 @default.
- NCIT_C103196 inSubset NCIT_C116978 @default.
- NCIT_C103196 inSubset NCIT_C176424 @default.
- NCIT_C103196 type Class @default.
- NCIT_C103196 isDefinedBy ncit.owl @default.
- NCIT_C103196 label "Fluorine F 18 4-L-fluoroglutamine (2S,4R)" @default.
- NCIT_C103196 subClassOf NCIT_C103196 @default.
- NCIT_C103196 subClassOf NCIT_C1446 @default.
- NCIT_C103196 subClassOf NCIT_C1908 @default.
- NCIT_C103196 subClassOf NCIT_C1909 @default.
- NCIT_C103196 subClassOf NCIT_C2124 @default.