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- NCIT_C103273 IAO_0000115 "An orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Upon oral administration, erdafitinib binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways and thus the inhibition of tumor cell proliferation and tumor cell death in FGFR-overexpressing tumor cells. FGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival." @default.
- NCIT_C103273 NCIT_A32 NCIT_C1909 @default.
- NCIT_C103273 NCIT_A7 NCIT_C17297 @default.
- NCIT_C103273 NCIT_NHC0 "C103273" @default.
- NCIT_C103273 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C103273 NCIT_P107 "Erdafitinib" @default.
- NCIT_C103273 NCIT_P108 "Erdafitinib" @default.
- NCIT_C103273 NCIT_P207 "C3641169" @default.
- NCIT_C103273 NCIT_P210 "1346242-81-6" @default.
- NCIT_C103273 NCIT_P302 "locally advanced or metastatic urothelial carcinoma" @default.
- NCIT_C103273 NCIT_P319 "890E37NHMV" @default.
- NCIT_C103273 NCIT_P322 "CTRP" @default.
- NCIT_C103273 NCIT_P322 "FDA" @default.
- NCIT_C103273 NCIT_P322 "GDC" @default.
- NCIT_C103273 NCIT_P329 "741845" @default.
- NCIT_C103273 NCIT_P330 "741845" @default.
- NCIT_C103273 NCIT_P375 "Erdafitinib" @default.
- NCIT_C103273 NCIT_P399 "741845" @default.
- NCIT_C103273 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C103273 referenceCount "2" @default.
- NCIT_C103273 hasExactSynonym "1,2-Ethanediamine, N1-(3,5-dimethoxyphenyl)-N2-(1-methylethyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl)-" @default.
- NCIT_C103273 hasExactSynonym "Balversa" @default.
- NCIT_C103273 hasExactSynonym "ERDAFITINIB" @default.
- NCIT_C103273 hasExactSynonym "Erdafitinib" @default.
- NCIT_C103273 hasExactSynonym "JNJ-42756493" @default.
- NCIT_C103273 inSubset NCIT_C116977 @default.
- NCIT_C103273 inSubset NCIT_C116978 @default.
- NCIT_C103273 inSubset NCIT_C128784 @default.
- NCIT_C103273 inSubset NCIT_C157711 @default.
- NCIT_C103273 inSubset NCIT_C157712 @default.
- NCIT_C103273 inSubset NCIT_C176424 @default.
- NCIT_C103273 inSubset NCIT_C177537 @default.
- NCIT_C103273 inSubset NCIT_C63923 @default.
- NCIT_C103273 type Class @default.
- NCIT_C103273 isDefinedBy ncit.owl @default.
- NCIT_C103273 label "Erdafitinib" @default.
- NCIT_C103273 subClassOf NCIT_C103273 @default.
- NCIT_C103273 subClassOf NCIT_C129824 @default.
- NCIT_C103273 subClassOf NCIT_C129825 @default.
- NCIT_C103273 subClassOf NCIT_C1404 @default.
- NCIT_C103273 subClassOf NCIT_C1908 @default.
- NCIT_C103273 subClassOf NCIT_C1909 @default.
- NCIT_C103273 subClassOf NCIT_C1967 @default.
- NCIT_C103273 subClassOf NCIT_C2189 @default.
- NCIT_C103273 subClassOf NCIT_C274 @default.
- NCIT_C103273 subClassOf NCIT_C471 @default.