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- NCIT_C103821 IAO_0000115 "A topical cellular cytokine solution containing a distinct combination of growth factors and cytokines secreted by and released from amnion-derived multipotent progenitor (AMP) cells, with potential immunomodulating and skin healing activities. The amnion-derived cellular cytokine solution (ACCS) contains near physiological levels of transforming growth factor beta, tissue inhibitor of metalloproteinase-1 (TIMP-1) and TIMP-2, as well as the angiogenesis factors platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and angiogenin that are normally found in healing wounds. Upon spraying the solution onto affected areas, the cytokines and growth factors in ACCS appear to increase the migration, proliferation and differentiation of both keratinocytes and fibroblasts; enhance the migration and phagocytosis of macrophages in wounds; and increase epithelialization. Together these processes may accelerate skin healing and tissue repair. Also, ACCS may be beneficial in the treatment of radiation burns of the skin." @default.
- NCIT_C103821 NCIT_NHC0 "C103821" @default.
- NCIT_C103821 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C103821 NCIT_P108 "Amnion-derived Cellular Cytokine Solution" @default.
- NCIT_C103821 NCIT_P208 "CL438304" @default.
- NCIT_C103821 NCIT_P329 "742567" @default.
- NCIT_C103821 NCIT_P330 "742567" @default.
- NCIT_C103821 NCIT_P399 "742567" @default.
- NCIT_C103821 normalizedInformationContent "100" @default.
- NCIT_C103821 referenceCount "1" @default.
- NCIT_C103821 hasExactSynonym "ACSS" @default.
- NCIT_C103821 hasExactSynonym "Amnion-derived Cellular Cytokine Solution" @default.
- NCIT_C103821 inSubset NCIT_C176424 @default.
- NCIT_C103821 type Class @default.
- NCIT_C103821 isDefinedBy ncit.owl @default.
- NCIT_C103821 label "Amnion-derived Cellular Cytokine Solution" @default.
- NCIT_C103821 subClassOf NCIT_C103821 @default.
- NCIT_C103821 subClassOf NCIT_C1908 @default.
- NCIT_C103821 subClassOf NCIT_C1909 @default.
- NCIT_C103821 subClassOf NCIT_C308 @default.