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- NCIT_C104004 IAO_0000115 "A topical formulation of the hydrochloride salt of the tropane alkaloid cocaine, with local anesthetic activity. Upon topical application of the cocaine hydrochloride solution to nasal mucous membranes, cocaine reversibly binds to and blocks the voltage-gated sodium channels in the neuronal cell membranes. By stabilizing neuronal membranes, cocaine inhibits the initiation and conduction of nerve impulses and produces a reversible loss of sensation." @default.
- NCIT_C104004 NCIT_NHC0 "C104004" @default.
- NCIT_C104004 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C104004 NCIT_P108 "Topical Cocaine Hydrochloride" @default.
- NCIT_C104004 NCIT_P208 "CL438387" @default.
- NCIT_C104004 NCIT_P329 "744401" @default.
- NCIT_C104004 NCIT_P330 "744401" @default.
- NCIT_C104004 NCIT_P399 "744401" @default.
- NCIT_C104004 normalizedInformationContent "100" @default.
- NCIT_C104004 referenceCount "1" @default.
- NCIT_C104004 hasExactSynonym "Topical Cocaine Hydrochloride" @default.
- NCIT_C104004 inSubset NCIT_C176424 @default.
- NCIT_C104004 type Class @default.
- NCIT_C104004 isDefinedBy ncit.owl @default.
- NCIT_C104004 label "Topical Cocaine Hydrochloride" @default.
- NCIT_C104004 subClassOf NCIT_C104004 @default.
- NCIT_C104004 subClassOf NCIT_C1908 @default.
- NCIT_C104004 subClassOf NCIT_C1909 @default.
- NCIT_C104004 subClassOf NCIT_C245 @default.
- NCIT_C104004 subClassOf NCIT_C78272 @default.