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- NCIT_C104269 IAO_0000115 "The hydrochloride salt form of a radioconjugate composed of a synthetic derivative of the amino acid methionine radiolabeled with fluoride F 18, with potential use as a tumor imaging agent during positron emission tomography (PET). Upon administration, fluorine F 18-labeled S-(3-fluoropropyl) homocysteine is preferentially taken up by tumor cells through an amino acid transporter, which is overexpressed by cancer cells. As tumor cells have a higher rate of proliferation than normal cells, these cancer cells have increased rates of protein synthesis and thus an increased demand for amino acids. This allows for visualization of tumors cells upon PET." @default.
- NCIT_C104269 NCIT_NHC0 "C104269" @default.
- NCIT_C104269 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C104269 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C104269 NCIT_P108 "Fluorine F 18-labeled S-(3-Fluoropropyl)homocysteine Hydrochloride" @default.
- NCIT_C104269 NCIT_P208 "CL445614" @default.
- NCIT_C104269 NCIT_P210 "1245941-98-3" @default.
- NCIT_C104269 NCIT_P319 "4G7MR2WS1V" @default.
- NCIT_C104269 NCIT_P322 "FDA" @default.
- NCIT_C104269 NCIT_P329 "744815" @default.
- NCIT_C104269 NCIT_P330 "744815" @default.
- NCIT_C104269 NCIT_P399 "744815" @default.
- NCIT_C104269 normalizedInformationContent "100" @default.
- NCIT_C104269 referenceCount "1" @default.
- NCIT_C104269 hasExactSynonym "(18F)-D-FPHCYS" @default.
- NCIT_C104269 hasExactSynonym "18F-FPM" @default.
- NCIT_C104269 hasExactSynonym "Fluorine F 18-labeled S-(3-Fluoropropyl)homocysteine Hydrochloride" @default.
- NCIT_C104269 hasExactSynonym "[(18)F]FPHCys" @default.
- NCIT_C104269 inSubset NCIT_C176424 @default.
- NCIT_C104269 inSubset NCIT_C63923 @default.
- NCIT_C104269 type Class @default.
- NCIT_C104269 isDefinedBy ncit.owl @default.
- NCIT_C104269 label "Fluorine F 18-labeled S-(3-Fluoropropyl)homocysteine Hydrochloride" @default.
- NCIT_C104269 subClassOf NCIT_C104269 @default.
- NCIT_C104269 subClassOf NCIT_C1446 @default.
- NCIT_C104269 subClassOf NCIT_C1908 @default.
- NCIT_C104269 subClassOf NCIT_C1909 @default.
- NCIT_C104269 subClassOf NCIT_C2124 @default.