Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C104275> ?p ?o ?g. }
Showing items 1 to 36 of
36
with 100 items per page.
- NCIT_C104275 IAO_0000115 "An immunoradioconjugate containing metuximab, an antibody fragment targeting the hepatocellular cancer (HCC)-associated antigen HAb18G/CD147, that is conjugated to the radioisotope iodine I 131, with potential antineoplastic activity. Upon administration, the metuximab moiety of licartin targets and binds to HAb18G/CD147 on HCC cells; upon internalization, the radioisotope I 131 delivers a cytotoxic dose of gamma radiation, thereby causing selective destruction of HAb18G/CD147-expressing cells. HAb18G/CD147, a member of CD147 family, is overexpressed in HCC and fibroblasts and its expression is associated with cancer cell progression and increased adhesion, invasion and metastasis." @default.
- NCIT_C104275 NCIT_A32 NCIT_C1909 @default.
- NCIT_C104275 NCIT_NHC0 "C104275" @default.
- NCIT_C104275 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C104275 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C104275 NCIT_P108 "Licartin" @default.
- NCIT_C104275 NCIT_P207 "C1722701" @default.
- NCIT_C104275 NCIT_P322 "GDC" @default.
- NCIT_C104275 NCIT_P329 "744892" @default.
- NCIT_C104275 NCIT_P330 "744892" @default.
- NCIT_C104275 NCIT_P375 "Licartin" @default.
- NCIT_C104275 NCIT_P399 "744892" @default.
- NCIT_C104275 normalizedInformationContent "100" @default.
- NCIT_C104275 referenceCount "1" @default.
- NCIT_C104275 hasExactSynonym "(131)I-labeled HAb18 F(ab')(2)" @default.
- NCIT_C104275 hasExactSynonym "Iodine I 131 Metuximab" @default.
- NCIT_C104275 hasExactSynonym "Iodine[131I] Metuximab" @default.
- NCIT_C104275 hasExactSynonym "Licartin" @default.
- NCIT_C104275 hasExactSynonym "[131I] mAb HAb18G/CD147" @default.
- NCIT_C104275 inSubset NCIT_C128784 @default.
- NCIT_C104275 inSubset NCIT_C157711 @default.
- NCIT_C104275 inSubset NCIT_C157712 @default.
- NCIT_C104275 inSubset NCIT_C176424 @default.
- NCIT_C104275 inSubset NCIT_C177537 @default.
- NCIT_C104275 type Class @default.
- NCIT_C104275 isDefinedBy ncit.owl @default.
- NCIT_C104275 label "Licartin" @default.
- NCIT_C104275 subClassOf NCIT_C104275 @default.
- NCIT_C104275 subClassOf NCIT_C1446 @default.
- NCIT_C104275 subClassOf NCIT_C1511 @default.
- NCIT_C104275 subClassOf NCIT_C1512 @default.
- NCIT_C104275 subClassOf NCIT_C1908 @default.
- NCIT_C104275 subClassOf NCIT_C1909 @default.
- NCIT_C104275 subClassOf NCIT_C2124 @default.
- NCIT_C104275 subClassOf NCIT_C307 @default.
- NCIT_C104275 subClassOf NCIT_C308 @default.