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- NCIT_C104415 IAO_0000115 "Autologous hematopoietic stem cells (HSCs) genetically modified to be resistant to infection by human immunodeficiency virus (HIV). Allogeneic human autologous HSCs are isolated and transduced ex vivo with three different anti-HIV genes. Upon infusion into the HIV-infected lymphoma patient, the gene-modified HIV-protected HSCs are resistant to HIV entry and replication thereby preventing HIV infection in these proliferating stem cells and any differentiated cells that they give rise to. This results in the formation of immune cells resistant to HIV which also may be able to destroy HIV-infected cells." @default.
- NCIT_C104415 NCIT_NHC0 "C104415" @default.
- NCIT_C104415 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C104415 NCIT_P108 "Gene-Modified HIV-Protected Hematopoietic Stem Cells" @default.
- NCIT_C104415 NCIT_P208 "CL445682" @default.
- NCIT_C104415 NCIT_P329 "745547" @default.
- NCIT_C104415 NCIT_P330 "745547" @default.
- NCIT_C104415 NCIT_P399 "745547" @default.
- NCIT_C104415 normalizedInformationContent "100" @default.
- NCIT_C104415 referenceCount "1" @default.
- NCIT_C104415 hasExactSynonym "Gene-Modified HIV-Protected Hematopoietic Stem Cells" @default.
- NCIT_C104415 inSubset NCIT_C176424 @default.
- NCIT_C104415 type Class @default.
- NCIT_C104415 isDefinedBy ncit.owl @default.
- NCIT_C104415 label "Gene-Modified HIV-Protected Hematopoietic Stem Cells" @default.
- NCIT_C104415 subClassOf NCIT_C104415 @default.
- NCIT_C104415 subClassOf NCIT_C119988 @default.
- NCIT_C104415 subClassOf NCIT_C142078 @default.
- NCIT_C104415 subClassOf NCIT_C154231 @default.
- NCIT_C104415 subClassOf NCIT_C1908 @default.
- NCIT_C104415 subClassOf NCIT_C1909 @default.
- NCIT_C104415 subClassOf NCIT_C1962 @default.
- NCIT_C104415 subClassOf NCIT_C201554 @default.
- NCIT_C104415 subClassOf NCIT_C307 @default.
- NCIT_C104415 subClassOf NCIT_C308 @default.