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- NCIT_C104745 IAO_0000115 "An orally available cancer cell stemness kinase inhibitor with potential antineoplastic activity. Even though the exact target has not been fully elucidated, amcasertib targets and inhibits one or more pathways involved in cancer stem cell survival. As a result, cancer stem cell (CSC) growth as well as heterogeneous cancer cell growth is inhibited. CSCs, self-replicating cells able to differentiate into heterogeneous cancer cells, appear to be responsible for both tumor relapse and metastasis." @default.
- NCIT_C104745 NCIT_A32 NCIT_C1909 @default.
- NCIT_C104745 NCIT_NHC0 "C104745" @default.
- NCIT_C104745 NCIT_P106 "Organic Chemical" @default.
- NCIT_C104745 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C104745 NCIT_P107 "Amcasertib" @default.
- NCIT_C104745 NCIT_P108 "Amcasertib" @default.
- NCIT_C104745 NCIT_P208 "CL445816" @default.
- NCIT_C104745 NCIT_P210 "1129403-56-0" @default.
- NCIT_C104745 NCIT_P319 "GLY8ABW25V" @default.
- NCIT_C104745 NCIT_P322 "CTRP" @default.
- NCIT_C104745 NCIT_P322 "FDA" @default.
- NCIT_C104745 NCIT_P322 "GDC" @default.
- NCIT_C104745 NCIT_P329 "746133" @default.
- NCIT_C104745 NCIT_P330 "746133" @default.
- NCIT_C104745 NCIT_P375 "Amcasertib" @default.
- NCIT_C104745 NCIT_P399 "746133" @default.
- NCIT_C104745 normalizedInformationContent "100" @default.
- NCIT_C104745 referenceCount "1" @default.
- NCIT_C104745 hasExactSynonym "AMCASERTIB" @default.
- NCIT_C104745 hasExactSynonym "Amcasertib" @default.
- NCIT_C104745 hasExactSynonym "BBI503" @default.
- NCIT_C104745 inSubset NCIT_C116977 @default.
- NCIT_C104745 inSubset NCIT_C116978 @default.
- NCIT_C104745 inSubset NCIT_C128784 @default.
- NCIT_C104745 inSubset NCIT_C157711 @default.
- NCIT_C104745 inSubset NCIT_C157712 @default.
- NCIT_C104745 inSubset NCIT_C176424 @default.
- NCIT_C104745 inSubset NCIT_C177537 @default.
- NCIT_C104745 inSubset NCIT_C63923 @default.
- NCIT_C104745 type Class @default.
- NCIT_C104745 isDefinedBy ncit.owl @default.
- NCIT_C104745 label "Amcasertib" @default.
- NCIT_C104745 subClassOf NCIT_C104745 @default.
- NCIT_C104745 subClassOf NCIT_C129824 @default.
- NCIT_C104745 subClassOf NCIT_C129825 @default.
- NCIT_C104745 subClassOf NCIT_C1404 @default.
- NCIT_C104745 subClassOf NCIT_C1908 @default.
- NCIT_C104745 subClassOf NCIT_C1909 @default.
- NCIT_C104745 subClassOf NCIT_C2189 @default.
- NCIT_C104745 subClassOf NCIT_C274 @default.
- NCIT_C104745 subClassOf NCIT_C471 @default.