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- NCIT_C105402 IAO_0000115 "An orally available inhibitor of spleen tyrosine kinase (Syk), with potential antineoplastic activity. Upon oral administration of entospletinib, this agent may inhibit the activity of Syk, which inhibits B-cell receptor (BCR) signaling and leads to an inhibition of tumor cell activation, migration, adhesion and proliferation. Syk, a non-receptor cytoplasmic, BCR-associated tyrosine kinase, is expressed in hematopoietic tissues and is often overexpressed in hematopoeitic malignancies." @default.
- NCIT_C105402 NCIT_A32 NCIT_C1909 @default.
- NCIT_C105402 NCIT_A7 NCIT_C18169 @default.
- NCIT_C105402 NCIT_NHC0 "C105402" @default.
- NCIT_C105402 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C105402 NCIT_P107 "Entospletinib" @default.
- NCIT_C105402 NCIT_P108 "Entospletinib" @default.
- NCIT_C105402 NCIT_P207 "C3642151" @default.
- NCIT_C105402 NCIT_P210 "1229208-44-9" @default.
- NCIT_C105402 NCIT_P319 "6I3O3W6O3B" @default.
- NCIT_C105402 NCIT_P322 "CTRP" @default.
- NCIT_C105402 NCIT_P322 "FDA" @default.
- NCIT_C105402 NCIT_P322 "GDC" @default.
- NCIT_C105402 NCIT_P329 "746910" @default.
- NCIT_C105402 NCIT_P330 "746910" @default.
- NCIT_C105402 NCIT_P375 "Entospletinib" @default.
- NCIT_C105402 NCIT_P399 "746910" @default.
- NCIT_C105402 normalizedInformationContent "100" @default.
- NCIT_C105402 referenceCount "1" @default.
- NCIT_C105402 hasExactSynonym "6-(1H-Indazol-6-yl)-N-(4-(morpholin-4-yl)phenyl)imidazo(1,2-a)pyrazin-8-amine" @default.
- NCIT_C105402 hasExactSynonym "ENTO" @default.
- NCIT_C105402 hasExactSynonym "ENTOSPLETINIB" @default.
- NCIT_C105402 hasExactSynonym "Entospletinib" @default.
- NCIT_C105402 hasExactSynonym "GS 9973" @default.
- NCIT_C105402 hasExactSynonym "GS-9973" @default.
- NCIT_C105402 hasExactSynonym "Imidazo(1,2-a)pyrazin-8-amine, 6-(1H-indazol-6-yl)-N-(4-(4-morpholinyl)phenyl)-" @default.
- NCIT_C105402 inSubset NCIT_C116977 @default.
- NCIT_C105402 inSubset NCIT_C116978 @default.
- NCIT_C105402 inSubset NCIT_C128784 @default.
- NCIT_C105402 inSubset NCIT_C157711 @default.
- NCIT_C105402 inSubset NCIT_C157712 @default.
- NCIT_C105402 inSubset NCIT_C176424 @default.
- NCIT_C105402 inSubset NCIT_C177537 @default.
- NCIT_C105402 inSubset NCIT_C63923 @default.
- NCIT_C105402 type Class @default.
- NCIT_C105402 isDefinedBy ncit.owl @default.
- NCIT_C105402 label "Entospletinib" @default.
- NCIT_C105402 subClassOf NCIT_C105402 @default.
- NCIT_C105402 subClassOf NCIT_C129824 @default.
- NCIT_C105402 subClassOf NCIT_C129825 @default.
- NCIT_C105402 subClassOf NCIT_C1404 @default.
- NCIT_C105402 subClassOf NCIT_C1908 @default.
- NCIT_C105402 subClassOf NCIT_C1909 @default.
- NCIT_C105402 subClassOf NCIT_C1967 @default.
- NCIT_C105402 subClassOf NCIT_C2189 @default.
- NCIT_C105402 subClassOf NCIT_C274 @default.
- NCIT_C105402 subClassOf NCIT_C471 @default.