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- NCIT_C105808 IAO_0000115 "A radioimmunoconjugate composed of a humanized recombinant monoclonal antibody directed against the extracellular dimerization domain of the tyrosine kinase receptor human epidermal growth factor-2 (HER-2) and linked to the gamma-emitting radioisotope indium In 111, with potential use in radioimaging. Upon administration, indium In 111 pertuzumab binds to HER-2. After binding and internalization into HER-2-expressing tumor cells, radioactive In 111 facilitates the detection of HER-2-expressing tumor cells using single photon emission computed tomography (SPECT). This may predict or evaluate the tumor's response to certain HER-2-targeting chemotherapeutics." @default.
- NCIT_C105808 NCIT_NHC0 "C105808" @default.
- NCIT_C105808 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C105808 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C105808 NCIT_P108 "Indium In 111 Pertuzumab" @default.
- NCIT_C105808 NCIT_P208 "CL447160" @default.
- NCIT_C105808 NCIT_P329 "747741" @default.
- NCIT_C105808 NCIT_P330 "747741" @default.
- NCIT_C105808 NCIT_P399 "747741" @default.
- NCIT_C105808 normalizedInformationContent "100" @default.
- NCIT_C105808 referenceCount "1" @default.
- NCIT_C105808 hasExactSynonym "111In-pertuzumab" @default.
- NCIT_C105808 hasExactSynonym "Indium In 111 Pertuzumab" @default.
- NCIT_C105808 inSubset NCIT_C176424 @default.
- NCIT_C105808 type Class @default.
- NCIT_C105808 isDefinedBy ncit.owl @default.
- NCIT_C105808 label "Indium In 111 Pertuzumab" @default.
- NCIT_C105808 subClassOf NCIT_C105808 @default.
- NCIT_C105808 subClassOf NCIT_C1446 @default.
- NCIT_C105808 subClassOf NCIT_C1511 @default.
- NCIT_C105808 subClassOf NCIT_C1512 @default.
- NCIT_C105808 subClassOf NCIT_C1908 @default.
- NCIT_C105808 subClassOf NCIT_C1909 @default.
- NCIT_C105808 subClassOf NCIT_C2124 @default.
- NCIT_C105808 subClassOf NCIT_C307 @default.
- NCIT_C105808 subClassOf NCIT_C308 @default.