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- NCIT_C106051 IAO_0000115 "A molecular genetic technique that depletes a biological sample of nucleosomal DNA and then subjects the non-nucleosome-associated DNA to next-generation sequencing. Since nucleosome disruption of chromatin is indicative of active sites of DNA transcription, this technique can isolate DNA sequences that are involved in transcriptional regulation. First, a sample is treated with formaldehyde to form DNA-protein crosslinks, followed by sample lysis and sonication. The processed sample is subjected to phenol/chloroform extraction and the DNA in the aqueous phase is analyzed using next-generation sequencing techniques." @default.
- NCIT_C106051 NCIT_NHC0 "C106051" @default.
- NCIT_C106051 NCIT_P106 "Molecular Biology Research Technique" @default.
- NCIT_C106051 NCIT_P108 "FAIRE-Seq" @default.
- NCIT_C106051 NCIT_P207 "C3830265" @default.
- NCIT_C106051 normalizedInformationContent "100" @default.
- NCIT_C106051 referenceCount "1" @default.
- NCIT_C106051 hasExactSynonym "FAIRE-Seq" @default.
- NCIT_C106051 hasExactSynonym "Formaldehyde-Assisted Isolation of Regulatory Elements Sequencing" @default.
- NCIT_C106051 type Class @default.
- NCIT_C106051 isDefinedBy ncit.owl @default.
- NCIT_C106051 label "FAIRE-Seq" @default.
- NCIT_C106051 subClassOf NCIT_C106051 @default.
- NCIT_C106051 subClassOf NCIT_C153598 @default.
- NCIT_C106051 subClassOf NCIT_C16203 @default.
- NCIT_C106051 subClassOf NCIT_C16623 @default.
- NCIT_C106051 subClassOf NCIT_C16847 @default.
- NCIT_C106051 subClassOf NCIT_C17565 @default.
- NCIT_C106051 subClassOf NCIT_C17632 @default.
- NCIT_C106051 subClassOf NCIT_C18881 @default.
- NCIT_C106051 subClassOf NCIT_C19235 @default.
- NCIT_C106051 subClassOf NCIT_C19770 @default.
- NCIT_C106051 subClassOf NCIT_C20368 @default.
- NCIT_C106051 subClassOf NCIT_C25218 @default.
- NCIT_C106051 subClassOf NCIT_C25294 @default.
- NCIT_C106051 subClassOf NCIT_C43431 @default.